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- Title
Diagnosis and therapy of coagulation disorders in operative orthopedics.
- Authors
Scharrer, I.
- Abstract
Patients suffering from von-Willebrand-disease or hemophilia A or B are the most common patients with coagulation disorders in orthopedic hospitals. Patients suffering from hemophilia A or B are treated with pure factor VIII or IX concentrates. We prefer recombinant products. The goals are normal levels of F VIII or F IX activity during the operation and postoperatively. In order to save costs the continuous infusion is recommended. Approximately 30 % of products and costs my be saved. The prevalence of von-Willebrand-disease is very high in Europe and USA (1 %). Typical presentation of these patients is the uncontrollable bleeding during an operation; typical is also the bleeding from mucous membranes. Patients with mild disorders are treated with DDAVP. Patients suffering from type 3 need substitution therapy with von-Willebrand-factor containing concentrates (for example Humate P).
- Publication
Der Orthopäde, 1999, Vol 28, Issue 4, p316
- ISSN
0085-4530
- Publication type
Article
- DOI
10.1007/PL00003613