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- Title
Nitrosative Stress and Type 2 Diabetic Patients.
- Authors
ALDOSSARY, AHMED TALIB YASSEN; MOHAMMED, ABDULLAH ALI; NAWFAL, AHMED JASIM; OBAID, AULA HASOON
- Abstract
The death of mammalian cells causing diabetes mellitus is linked to nitrosative stress rates (DM). Through all antioxidant enzyme pathways (SOD, CAT, GPx, GSH) and full oxidative capacity (TAC) that cause peroxidative destruction of carbohydrates, proteins, lipids, and nucleic acids that could be used as DM biological markers, both forms 1 and 2 DM involve major oxidative and nitrosative stress coupled with severe changes. Many cardiovascular events, including obesity, hyperlipidemia, diabetes, hypertension, and impaired glucose metabolism, describe Metabolic Syndrome (MS) as a global public health problem. Oxidative damage and cellular redox imbalance are the relationship between MS and related diseases, all related to the existence of chronic inflammatory conditions that classify MS. Oxidative (nitrosative) stress-induced consequences of diabetes, including stroke, neuropathy, retinopathy, and nephropathy. The association between type 2 diabetes and oxidative or nitrosative stress is discussed in this review.
- Subjects
NITROSATION; TYPE 2 diabetes diagnosis; PEROXIDATION; OXIDATIVE stress; BIOMARKERS; METABOLIC syndrome
- Publication
International Journal of Pharmaceutical Research (09752366), 2021, Vol 13, Issue 2, p2180
- ISSN
0975-2366
- Publication type
Article
- DOI
10.31838/ijpr/2021.13.02.283