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- Title
β-Lactamase Producing Escherichia coli Encoding bla CTX-M and bla CMY Genes in Chicken Carcasses from Egypt.
- Authors
Abo-Almagd, Elham Elsayed; Sabala, Rana Fahmi; Abd-Elghany, Samir Mohammed; Jackson, Charlene R.; Ramadan, Hazem; Imre, Kálmán; Morar, Adriana; Herman, Viorel; Sallam, Khalid Ibrahim
- Abstract
Escherichia coli with multidrug resistance and β-lactamase genes may constitute a great public health hazard due to the potential for their transmission to humans through the food chain. This study determined the prevalence, antibiotic resistance profiles, phylogroups, and β-lactamase genes of E. coli isolates from chicken carcasses marketed in Mansoura, Egypt. Interestingly, E. coli was detected in 98% (98/100) of the chicken carcasses examined, which seemed among the highest contamination rates by E. coli worldwide. From the 425 genetically verified uidA gene-positive E. coli, 85 isolates were further studied for antimicrobial resistance profiles, phylogroups, and β-lactamase genes. Interestingly, 89.41% of E. coli (76/85) strains tested against 24 different antibiotics were multidrug-resistant. Of the examined 85 E. coli isolates, 22 (25.88%) isolates harbored blaCTX-M and were resistant to ampicillin, cefazoline, and ceftriaxone, while three of them were resistant to ceftazidime besides. Nine (10.59%) E. coli strains harbored AmpC- β-lactamase blaCMY and were resistant to ampicillin. One isolate co-carried blaCMY and blaCTX-M genes, though it was negative for the blaTEM gene. Of the 35 isolates that harbored either extended-spectrum β-lactamase (ESBL) and/or AmpC β-lactamase genes, six strains (17.14%) were assigned to pathogenic phylogroup F and one to phylogroup E, whereas 28 (80%) isolates belonged to commensal phylogenetic groups.
- Subjects
EGYPT; MANSURAH (Egypt); ESCHERICHIA coli; MULTIDRUG resistance; CATTLE carcasses; GENES; CHICKEN as food; DRUG resistance in microorganisms
- Publication
Foods, 2023, Vol 12, Issue 3, p598
- ISSN
2304-8158
- Publication type
Article
- DOI
10.3390/foods12030598