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- Title
The Enterics for Global Health (EFGH) Shigella Surveillance Study in Bangladesh.
- Authors
Khanam, Farhana; Islam, Md Taufiqul; Bhuiyan, Taufiqur Rahman; Hossen, Md Ismail; Rajib, Md Nazmul Hasan; Haque, Shahinur; Ireen, Mahzabeen; Qudrat-E-Khuda, Syed; Biswas, Prasanta Kumar; Bhuiyan, Md Amirul Islam; Islam, Kamrul; Rahman, Nazia; Raz, S M Azadul Alam; Mosharraf, Md Parvej; Bhuiyan, Md Elias Shawon; Islam, Sadia; Ahmed, Dilruba; Ahmmed, Faisal; Zaman, Khalequ; Clemens, John D
- Abstract
Background Shigella is an important cause of diarrhea in Bangladeshi children <5 years of age, with an incidence rate of 4.6 per 100 person-years. However, the report was more than a decade old, and data on Shigella consequences are similarly outdated and heterogeneously collected. Methods Facility-based disease surveillance is planned to be carried out under the Enterics for Global Health (EFGH) Shigella Surveillance Study consortium for 2 years with aims to optimize and standardize laboratory techniques and healthcare utilization and coverage survey, clinical and anthropometric data collection, safety monitoring and responsiveness, and other related activities. The EFGH is a cohesive network of multidisciplinary experts, capable of operating in concert to conduct the study to generate data that will pave the way for potential Shigella vaccine trials in settings with high disease burden. The study will be conducted within 7 country sites in Asia, Africa, and Latin America. Conclusions We outline the features of the Bangladesh site as part of this multisite surveillance network to determine an updated incidence rate and document the consequences of Shigella diarrhea in children aged 6–35 months, which will help inform policymakers and to implement the future vaccine trials.
- Subjects
BANGLADESH; SHIGELLOSIS; SHIGELLA; WORLD health; VACCINE trials; LABORATORY techniques; ACQUISITION of data
- Publication
Open Forum Infectious Diseases, 2024, Vol 11, pS76
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofad653