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- Title
Romatoid artrit'te kemik sintigrafisi bulguları, DAS28 skoru ve biyokimyasal parametrelerin karşılaştırılması.
- Authors
Karaçavuş, Seyhan; Uçar, Mehmet; Geçer, Mehmet Fatih; Balbaloğlu, Özlem; Nas, Ömer; Sarp, Ümit
- Abstract
Background: Rheumatoid arthritis (RA) is a chronic inflammatory and autoimmune disease characterized by progressive damage of joints. In this study, we investigated the relationship between the disease activity scores and bone scan findings and biochemical parameters in patients with RA. Method: Sixty two patients (F/M: 44/8, age 51,8±11,1; range 31-77) diagnosed with RA according to the American College of Rheumatology (ACR) criteria were included in the study. All patients were divided to two groups regarding their DAS28 score; Group 1 was DAS28 score≥3,2 and Group 1 was DAS28 score<3,2. The whole body bone scintigraphy with Tc99m-MDP (TVKS) was performed all subject. A increased uptake on any joint in blood pool phase and late static phase of bone scan was evaluated as a positive result. Laboratory data including the erythrocyte sedimentation rate and C-reactive protein were recorded. The clinical parameters were assessed by the Health Assessment Questionnaire (HAQ) and Ritchie articular index (RAİ). Results: The mean number of peripheral joint involvement was higher in Group 1 than in Group 2 (11/8; p<0.05). Number of joint involvement (r=0.5,p=0.019) and biochemical parameters (r=0.7,p<0.001) were increased with clinical score in Higher disease activity score group. In 6 of 13 patients of lower DAS28 group, number of peripheral joint involvement were similar to high DAS28 group. Conclusion: Whole body bone scintigraphy is a cheap and easy method, that contributes a lot to the clinical approach in patients with rheumatoid arthritis, in the evaluation of peripheral joints in a single session and determining the joints those not expressing significant clinical findings yet.
- Subjects
BLOOD sedimentation; C-reactive protein; CLINICAL pathology; DIAGNOSIS of musculoskeletal system diseases; QUESTIONNAIRES; RADIONUCLIDE imaging; RHEUMATOID arthritis; SYMPTOMS
- Publication
Journal of Harran University Medical Faculty / Harran Üniversitesi Tıp Fakültesi Dergisi, 2015, Vol 12, Issue 2, p255
- ISSN
1304-9623
- Publication type
Article