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- Title
BETA THALASSEMIA; IMPAIRED GLUCOSE TOLERANCE IN CHILDREN WITH BLOOD TRANSFUSION DEPENDENT BETA THALASSEMIA.
- Authors
Ahmed, Iqbal; Sadiq, Muhammad Ammar; Arshad, Umair; Hafiz Muhammad Anwar ul Haq; Tabassum, Sobia; Sabir, Arshia; Hafiz Muhammad Ejaz ul Haq
- Abstract
Background: Inadequate Blood Transfusion is responsible for various problems in children with Thalasseima. On the other hand, repeated transfusions are related with hazards. About 25-50% of the children with thalassemia major have impaired glucose tolerance (IGT) or diabetes. Objectives: To find out the frequency of IGT in children with blood transfusion dependent β thalassemia. Study Design: Descriptive analytical study. Setting: Department of Pediatrics, Shahida Islam Teaching Hospital, Lodhran. Period: 1st July 2017 to 31st December 2017. Material and Methods: Known 120 cases of beta Thalassemia major children between 3-17 years of age that were regularly transfused. Demographics, disease history and personal information regarding all the patients were collected. Glucose tolerance test was performed and Serum ferritin levels were measured. Results were analyzed by SPSS software version 20.0. Results: There were 78 (65.0%) children between 3-10 years and 42 (35.0%) between 11-17 years. There were 70(58.3) male and 50 (41.7%) female. Frequency of impaired glucose tolerance was noted in 15 (12.5%). Conclusion: Frequency of IGT is high amongst children with thalassemia major having regular blood transfusions.
- Subjects
BETA-Thalassemia; GLUCOSE tolerance tests; BLOOD transfusion
- Publication
Professional Medical Journal, 2018, Vol 25, Issue 9, p1402
- ISSN
1024-8919
- Publication type
Article
- DOI
10.29309/TPMJ/18.4701