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Murine embryonal carcinoma hybrids: Decreased ability to spontaneously differentiate as a dominant trait.
- Published in:
- Journal of Cellular Physiology, 1981, v. 109, n. 2, p. 195, doi. 10.1002/jcp.1041090202
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- Publication type:
- Article
Editorial: Drug Development for Parasite-Induced Diarrheal Diseases.
- Published in:
- 2017
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- Publication type:
- Editorial
Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 6, p. 744, doi. 10.3390/ph15060744
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- Publication type:
- Article
Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease.
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- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 10, p. 1, doi. 10.1371/journal.pntd.0009819
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- Publication type:
- Article
Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 9, p. 1, doi. 10.1371/journal.pntd.0008726
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- Publication type:
- Article
Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000651
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- Publication type:
- Article
Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 3, p. 1, doi. 10.1371/journal.pntd.0000648
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- Publication type:
- Article
Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000651
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- Publication type:
- Article
Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 3, p. 1, doi. 10.1371/journal.pntd.0000648
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- Publication type:
- Article
Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 7, p. 1, doi. 10.1371/journal.pntd.0000478
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- Publication type:
- Article
Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 7, p. 1, doi. 10.1371/journal.pntd.0000478
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- Publication type:
- Article
SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 6, p. 1, doi. 10.1371/journal.pntd.0000449
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- Publication type:
- Article
SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 6, p. 1
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- Publication type:
- Article
High-Throughput Analysis of an RNAi Library Identifies Novel Kinase Targets in Trypanosoma brucei.
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- Chemical Biology & Drug Design, 2011, v. 78, n. 3, p. 454, doi. 10.1111/j.1747-0285.2011.01156.x
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- Publication type:
- Article
Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines.
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- Parasitology Research, 2023, v. 122, n. 12, p. 2751, doi. 10.1007/s00436-023-07993-2
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- Publication type:
- Article
Leishmania major protein disulfide isomerase as a drug target.
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- Parasitology Research, 2012, v. 110, n. 5, p. 1911, doi. 10.1007/s00436-011-2717-5
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- Article
World Class Parasites: Vol. X, Schistosomiasis.
- Published in:
- 2006
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- Publication type:
- Book Review
Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 1, p. 1, doi. 10.1371/journal.pntd.0004356
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- Publication type:
- Article
Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 7, p. 1, doi. 10.1371/journal.pntd.0003916
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- Publication type:
- Article
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003878
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003878
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- Publication type:
- Article
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003588
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- Publication type:
- Article
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003588
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- Publication type:
- Article
Hormone receptors in hepatoblastoma: a demonstration of both estrogen and progesterone receptors.
- Published in:
- 1982
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- Publication type:
- journal article
A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.
- Published in:
- Nature Medicine, 2012, v. 18, n. 6, p. 956, doi. 10.1038/nm.2758
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- Publication type:
- Article
Identification of Genomic Responses to Collagen Binding by Trophozoites of Entamoeba histolytica.
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- Journal of Infectious Diseases, 2004, v. 190, n. 3, p. 448, doi. 10.1086/422323
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- Publication type:
- Article
Discovery of Trypanocidal Compounds by Whole Cell HTS of Trypanosoma brucei.
- Published in:
- Chemical Biology & Drug Design, 2006, v. 67, n. 5, p. 355, doi. 10.1111/j.1747-0285.2006.00389.x
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- Publication type:
- Article
Global identification of peptidase specificity by multiplex substrate profiling.
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- Nature Methods, 2012, v. 9, n. 11, p. 1095, doi. 10.1038/nmeth.2182
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- Publication type:
- Article
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005680
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- Publication type:
- Article
Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 12, p. 1, doi. 10.1371/journal.pntd.0005234
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- Publication type:
- Article
Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 8, p. 1, doi. 10.1371/journal.pntd.0004893
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- Publication type:
- Article
TLTF in Cerebrospinal Fluid for Detection and Staging of <i>T. b. gambiense</i> Infection.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079281
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- Publication type:
- Article
Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046172
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- Publication type:
- Article
Early Invasion of Brain Parenchyma by African Trypanosomes.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043913
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- Publication type:
- Article
A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni.
- Published in:
- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004413
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- Publication type:
- Article
Recent Insights into the Structure and Function of a Larval Proteinase Involved in Host Infection by a Multicellular Parasite.
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- Proceedings of the Society for Experimental Biology & Medicine, 1991, v. 197, n. 2, p. 119, doi. 10.3181/00379727-197-43233
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- Publication type:
- Article
The common gamma chain cytokines interleukin (IL)-2 and IL-7 indirectly modulate blood fluke development via effects on CD4+ T cells.
- Published in:
- 2006
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- Publication type:
- journal article
The Common γ Chain Cytokines Interleukin (IL)-2 and IL-7 Indirectly Modulate Blood Fluke Development via Effects on CD4<sup>+</sup> T Cells.
- Published in:
- Journal of Infectious Diseases, 2006, v. 194, n. 11, p. 1609, doi. 10.1086/508896
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- Publication type:
- Article
Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms.
- Published in:
- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 10, p. 1, doi. 10.1371/journal.pntd.0006923
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- Publication type:
- Article
The diverse roles of cysteine proteases in parasites and their suitability as drug targets.
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- PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005639
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- Publication type:
- Article
Update on drug development targeting parasite cysteine proteases.
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- PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005850
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- Publication type:
- Article
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006132
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- Publication type:
- Article
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006104
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- Publication type:
- Article
First report on prevalence of SARS-CoV-2 infection among health-care workers in Nicaragua.
- Published in:
- PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0246084
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- Publication type:
- Article
High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi.
- Published in:
- Microorganisms, 2020, v. 8, n. 4, p. 472, doi. 10.3390/microorganisms8040472
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- Publication type:
- Article
Molecular dissection of chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.
- Published in:
- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 5, p. 1, doi. 10.1371/journal.pntd.0007980
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- Publication type:
- Article
Genetic analysis of basophil function in vivo.
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- Nature Immunology, 2011, v. 12, n. 6, p. 527, doi. 10.1038/ni.2036
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- Publication type:
- Article
Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis.
- Published in:
- Pathogens, 2024, v. 13, n. 10, p. 850, doi. 10.3390/pathogens13100850
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- Publication type:
- Article