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- Title
Correction: Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain.
- Authors
Saito, Ryota; Goto, Masaru; Katakura, Shun; Ohba, Taro; Kawata, Rena; Nagatsu, Kazuki; Higashi, Shoko; Kurisu, Kaede; Matsumoto, Kaori; Ohtsuka, Kouta
- Abstract
This document is a correction notice for an article titled "Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain." The correction addresses errors in Figure 3, the Results and Discussion section, and Table 1. The corrected Figure 3 shows interactions between 4b and RTA, while the corrected sentence in the Results and Discussion section describes the hydrogen bonds made by the carbonyl group of the Cbz in 4b. Additionally, the corrected Table 1 swaps the IC50 values for compounds 4a and 4b. The correct IC50 value for 4a is 485±33 μM, and for 4b it is 33.4±2.7 μM. The authors of the article are Ryota Saito, Masaru Goto, Shun Katakura, Taro Ohba, Rena Kawata, Kazuki Nagatsu, Shoko Higashi, Kaede Kurisu, Kaori Matsumoto, and Kouta Ohtsuka.
- Subjects
RICIN; SMALL molecules; CARBONYL group
- Publication
PLoS ONE, 2024, Vol 19, Issue 5, p1
- ISSN
1932-6203
- Publication type
Correction Notice
- DOI
10.1371/journal.pone.0304251