We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Copper-Mediated Synthesis of 1,2,3-Triazoles from N-Tosylhydrazones and Anilines.
- Authors
Chen, Zhengkai; Yan, Qiangqiang; Liu, Zhanxiang; Xu, Yiming; Zhang, Yuhong
- Abstract
NNNifty targets: In a straightforward copper‐mediated synthesis of 1,4‐disubstituted and 1,4,5‐trisubstituted 1,2,3‐triazoles, readily available aniline and N‐tosylhydrazone substrates underwent cyclization through CN and NN bond formation (see scheme; Piv=pivaloyl, Ts=p‐toluenesulfonyl). This method enables the preparation of 1,2,3‐triazoles with high efficiency under mild conditions without the use of azides.
- Subjects
TRIAZOLES synthesis; TRIAZOLE derivatives; HYDRAZONE derivatives; COPPER spectra; CHEMICAL bonds
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 50, p13324
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201306416