Found: 51
Select item for more details and to access through your institution.
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.837534
- By:
- Publication type:
- Article
Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.
- Published in:
- EMBO Reports, 2004, v. 5, n. 6, p. 584, doi. 10.1038/sj.embor.7400169
- By:
- Publication type:
- Article
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance.
- Published in:
- Journal of Physiology, 2007, v. 584, n. 3, p. 983, doi. 10.1113/jphysiol.2007.141358
- By:
- Publication type:
- Article
Different flecainide sensitivity of hNa<sub>v</sub> 1.4 channels and myotonic mutants explained by state-dependent block.
- Published in:
- Journal of Physiology, 2004, v. 554, n. 2, p. 321, doi. 10.1113/jphysiol.2003.046995
- By:
- Publication type:
- Article
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene.
- Published in:
- Journal of Human Genetics, 2013, v. 58, n. 9, p. 581, doi. 10.1038/jhg.2013.58
- By:
- Publication type:
- Article
Structural requisites of 2-(p-chlorophenoxy) propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.
- Published in:
- British Journal of Pharmacology, 2003, v. 139, n. 7, p. 1255, doi. 10.1038/sj.bjp.0705364
- By:
- Publication type:
- Article
Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor.
- Published in:
- British Journal of Pharmacology, 2003, v. 139, n. 3, p. 575, doi. 10.1038/sj.bjp.0705284
- By:
- Publication type:
- Article
Dualistic actions of cromakalim and new potent 2H-1,4-benzoxazine derivatives on the native skeletal muscle K[subSTP] channel.
- Published in:
- British Journal of Pharmacology, 2003, v. 139, n. 2, p. 255, doi. 10.1038/sj.bjp.0705233
- By:
- Publication type:
- Article
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na<sup>+</sup> channels enhancing the antimyotonic activity in vivo.
- Published in:
- British Journal of Pharmacology, 2001, v. 134, n. 7, p. 1523, doi. 10.1038/sj.bjp.0704366
- By:
- Publication type:
- Article
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine.
- Published in:
- British Journal of Pharmacology, 2001, v. 132, n. 5, p. 1047, doi. 10.1038/sj.bjp.0703907
- By:
- Publication type:
- Article
Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels.
- Published in:
- British Journal of Pharmacology, 1998, v. 125, n. 3, p. 477, doi. 10.1038/sj.bjp.0702107
- By:
- Publication type:
- Article
Effects of chronic growth hormone treatment in aged rats on the biophysical and pharmacological properties of skeletal muscle chloride channels.
- Published in:
- British Journal of Pharmacology, 1997, v. 121, n. 3, p. 369, doi. 10.1038/sj.bjp.0701129
- By:
- Publication type:
- Article
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers.
- Published in:
- Journal of Heterocyclic Chemistry, 2007, v. 44, n. 5, p. 1099, doi. 10.1002/jhet.5570440519
- By:
- Publication type:
- Article
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography.
- Published in:
- Scientific Reports, 2016, p. 20061, doi. 10.1038/srep20061
- By:
- Publication type:
- Article
Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129686
- By:
- Publication type:
- Article
Effects of Pleiotrophin Overexpression on Mouse Skeletal Muscles in Normal Loading and in Actual and Simulated Microgravity.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072028
- By:
- Publication type:
- Article
Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069551
- By:
- Publication type:
- Article
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065167
- By:
- Publication type:
- Article
Splicing of the rSlo Gene Affects the Molecular Composition and Drug Response of Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in Skeletal Muscle.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040235
- By:
- Publication type:
- Article
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs.
- Published in:
- Chirality, 2010, v. 22, n. 3, p. 299, doi. 10.1002/chir.20741
- By:
- Publication type:
- Article
Hydroxylated Analogs of Mexiletine as Tools for Structural-Requirements Investigation of the Sodium Channel Blocking Activity.
- Published in:
- Archiv der Pharmazie, 2010, v. 343, n. 6, p. 325, doi. 10.1002/ardp.200900218
- By:
- Publication type:
- Article
Mechanism of Interaction of Niflumic Acid with Heterologously Expressed Kidney CLC-K Chloride Channels.
- Published in:
- Journal of Membrane Biology, 2007, v. 216, n. 2/3, p. 73, doi. 10.1007/s00232-007-9034-z
- By:
- Publication type:
- Article
Skeletal muscle ClC-1 chloride channels in health and diseases.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2020, v. 472, n. 7, p. 961, doi. 10.1007/s00424-020-02376-3
- By:
- Publication type:
- Article
Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 367, n. 3, p. 318, doi. 10.1007/s00210-002-0669-0
- By:
- Publication type:
- Article
ClC-1 chloride channels: state-of-the-art research and future challenges.
- Published in:
- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00156
- By:
- Publication type:
- Article
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita.
- Published in:
- NeuroMolecular Medicine, 2015, v. 17, n. 3, p. 285, doi. 10.1007/s12017-015-8356-8
- By:
- Publication type:
- Article
Change of chloride ion channel conductance is an early event of slow‐to‐fast fibre type transition during unloading‐induced muscle disuse.
- Published in:
- Brain: A Journal of Neurology, 2002, v. 125, n. 7, p. 1510, doi. 10.1093/brain/awf162
- By:
- Publication type:
- Article
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies.
- Published in:
- FASEB Journal, 2016, v. 30, n. 10, p. 3285, doi. 10.1096/fj.201500079R
- By:
- Publication type:
- Article
Pharmacovigilance‐pharmacological investigations on sulfonylureas and glinides‐induced atrophy in skeletal muscle (1142.5).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1142.5
- By:
- Publication type:
- Article
Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery.
- Published in:
- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00121
- By:
- Publication type:
- Article
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres.
- Published in:
- Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00155
- By:
- Publication type:
- Article
The impact of SARS-CoV-2 on skeletal muscles.
- Published in:
- Acta Myologica, 2020, v. 39, n. 4, p. 307, doi. 10.36185/2532-1900-034
- By:
- Publication type:
- Article
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K<sup>+</sup>-deficient rats.
- Published in:
- FASEB Journal, 2004, v. 18, n. 6, p. 760, doi. 10.1096/fj.03-0722fje
- By:
- Publication type:
- Article
Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle.
- Published in:
- FASEB Journal, 2003, v. 17, n. 13, p. 1916
- By:
- Publication type:
- Article
Effect of microgravity on gene expression in mouse brain.
- Published in:
- Experimental Brain Research, 2008, v. 191, n. 3, p. 289, doi. 10.1007/s00221-008-1523-5
- By:
- Publication type:
- Article
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT<sub>1</sub> receptor blockers valsartan and olmesartan.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Taurine: the appeal of a safe amino acid for skeletal muscle disorders.
- Published in:
- Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0610-1
- By:
- Publication type:
- Article
Taurine: the appeal of a safe amino acid for skeletal muscle disorders.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research.
- Published in:
- Journal of Physiology, 2017, v. 595, n. 16, p. 5403, doi. 10.1113/JP274645
- By:
- Publication type:
- Article
Redox homeostasis, oxidative stress and disuse muscle atrophy.
- Published in:
- Journal of Physiology, 2011, v. 589, n. 9, p. 2147, doi. 10.1113/jphysiol.2010.203232
- By:
- Publication type:
- Article
The K<sub>ATP</sub> channel is a molecular sensor of atrophy in skeletal muscle.
- Published in:
- Journal of Physiology, 2010, v. 588, n. 5, p. 773, doi. 10.1113/jphysiol.2009.185835
- By:
- Publication type:
- Article
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb-unloaded mice.
- Published in:
- Experimental Physiology, 2010, v. 95, n. 2, p. 331, doi. 10.1113/expphysiol.2009.050245
- By:
- Publication type:
- Article
Dual Action of Mexiletine and Its Pyrroline Derivatives as Skeletal Muscle Sodium Channel Blockers and Anti-oxidant Compounds: Toward Novel Therapeutic Potential.
- Published in:
- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00907
- By:
- Publication type:
- Article
Stereospecific synthesis of para-hydroxymexiletine and sodium channel blocking activity evaluation.
- Published in:
- Chirality, 2004, v. 16, n. 2, p. 72
- By:
- Publication type:
- Article
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within the CBS2 domain and the C‐terminal peptide of the ClC‐1 channel.
- Published in:
- Human Mutation, 2018, v. 39, n. 9, p. 1273, doi. 10.1002/humu.23581
- By:
- Publication type:
- Article
On the Metabolically Active Form of Metaglidasen: Improved Synthesis and Investigation of Its Peculiar Activity on Peroxisome Proliferator-Activated Receptors and Skeletal Muscles.
- Published in:
- ChemMedChem, 2015, v. 10, n. 3, p. 555, doi. 10.1002/cmdc.201402462
- By:
- Publication type:
- Article
Acetazolamide opens the muscular K.
- Published in:
- Annals of Neurology, 2000, v. 48, n. 3, p. 304, doi. 10.1002/1531-8249(200009)48:3<304::AID-ANA4>3.0.CO;2-A
- By:
- Publication type:
- Article
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice.
- Published in:
- 1995
- By:
- Publication type:
- journal article