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- Title
Comparison of patterns of infarction in TB and cryptococcal meningitis.
- Authors
Kumar, Mritunjai; Dhar, Nikita; Tiwari, Ashutosh; Siddiqui, Md Sabah
- Abstract
Background To compare the frequency and patterns of stroke, the specificity of tubercular zone (TBZ) infarction and its effect on outcomes in TB (TBM) and cryptococcal meningitis (CM). Methods This retrospective study was conducted at two tertiary centres in India from May 2018 to July 2020. Sixty-one patients with TBM and 22 with CM were included. The primary outcome was the proportions of TBM and CM patients with infarction. Secondary outcomes included the anatomical locations of infarction and in-hospital mortality. Results Infarction was noted in 52.5% of patients with TBM and in 54.5% of those with CM (p=0.87), with caudate head infarcts in 9.4% vs 41.7% (p=0.01), cerebellar in 9.4% vs 33.3% (p=0.05), thalamic in 25% vs 0% and lobar in 28.1% vs 0%, respectively. In TBM, the infarcts were located in the TBZ in 3 (9.4%), in the ischaemic zone in 23 (71.9%), while 6 (18.8%) patients showed infarcts in both, while in CM, the infarcts were in 0 (0%), 6 (50%) and 6 (50%) patients, respectively. Infarcts were not associated with in-hospital mortality, either in TBM or CM. Conclusion Caudate head and cerebellar infarction was more common in CM, while thalamic and lobar infarcts were more frequent in TBM. TBZ infarcts were not specific to TBM.
- Subjects
INDIA; INFARCTION; MENINGITIS; HOSPITAL mortality
- Publication
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2021, Vol 115, Issue 10, p1160
- ISSN
0035-9203
- Publication type
Article
- DOI
10.1093/trstmh/trab070