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- Title
Adventures in drug disposition: pas seulement pâté de foie.
- Authors
Sitar, Daniel S.
- Abstract
Interindividual variability in drug disposition and effect has served to confound the optimization of drug therapy. Over my career, I have focused on delineating mechanisms that contribute to this variability, with the goal of improving the benefit : risk ratio when drug therapy is chosen as an intervention strategy. In this manuscript, I present some of our experimental findings that I believe have contributed to an increased understanding of variability in drug disposition and efficacy.
- Subjects
DRUGS; DRUG therapy; THERAPEUTICS; PHARMACOLOGY; MEDICINE
- Publication
Canadian Journal of Physiology & Pharmacology, 2007, Vol 85, Issue 12, p1215
- ISSN
0008-4212
- Publication type
Article
- DOI
10.1139/Y07-121