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- Title
Riding the Wave of Ambivalence in Cell Biology.
- Authors
Emanuele, Sonia; Giuliano, Michela
- Abstract
This document, published in the International Journal of Molecular Sciences, discusses the concept of dual function molecules in cell biology. It explains that many molecules in cells can have opposing roles depending on their context, pathway, or location within the cell. The document provides examples of proteins with dual functions, such as p53 and cyclin-dependent kinase inhibitors. It also explores the dual roles of factors like c-Jun-NH(2)-terminal kinase (JNK), reactive oxygen species (ROS), and glucocorticoid treatment in cancer cells. The authors conclude that understanding these dual functions is crucial for studying cell fate decisions.
- Subjects
CYTOLOGY; TRANSCRIPTION factors; CELL metabolism; AMBIVALENCE; APOPTOSIS; POST-translational modification
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 13, p7348
- ISSN
1661-6596
- Publication type
Editorial
- DOI
10.3390/ijms25137348