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- Title
Prévalence et caractéristiques de l'association de neuroleptiques chez une cohorte de patients souffrant de troubles psychotiques.
- Authors
Huguelet, Philippe; Khan, Aqal Nawaz; Morand-Collomb, Sophie; Mohr, Sylvia; Etter, Manuela
- Abstract
<bold>Objectives: </bold>Combined antipsychotic drugs are often prescribed, despite a lack of objective supporting data. Therefore, it is especially important to determine the scope of this practice and to better understand the characteristics of affected patients to identify which associations to study first.<bold>Method: </bold>We studied patients with psychotic disorders followed for at least 1 year at an outpatient psychiatric clinic in Geneva (n = 253). We collected data on prescriptions given at baseline and during that period, as well as sociodemographic and clinical data.<bold>Results: </bold>During the follow-up period, 36% of patients were prescribed a neuroleptic. These patients differ by negative changing characteristics: less activity, financial assistance, nursing home placement, and numerous admissions with earlier onset of disorder. Three-quarters of patients did not change treatment during that period. Treatment stability is associated with treatment compliance and lack of hospital admission during the follow-up period.<bold>Conclusion: </bold>Without any scientific substantiation, patients with negative changing characteristics are often prescribed neuroleptics. Such treatment options are likely relatively inefficient strategies. Moreover, this practice risks further complicating patients who are already characterized by negative elements.
- Subjects
DRUG therapy for psychoses; ANTIPSYCHOTIC agents; DRUG therapy; COGNITION disorders; DEMOGRAPHY; LONGITUDINAL method; PSYCHOSES; DISEASE prevalence
- Publication
Canadian Journal of Psychiatry, 2006, Vol 51, Issue 11, p774
- ISSN
0706-7437
- Publication type
journal article
- DOI
10.1177/070674370605101207