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- Title
Bipolar II disorder: an overview of recent developments.
- Authors
Hadjipavlou, George; Mok, Hiram; Yatham, Lakshmi N.
- Abstract
<bold>Objective: </bold>Recent research on the epidemiology, clinical course, diagnosis, and treatment of bipolar II disorder (BD II) stands to have a considerable impact on clinical practice. This paper reviews these developments.<bold>Method: </bold>We conducted a Pubmed search, focusing on the period from January 1, 1994, to August 31, 2004. Articles deemed directly relevant to the epidemiology, course, diagnosis, and management of BD II were considered.<bold>Results: </bold>The prevalence of BD II is likely higher than previously suggested. Systematic probing for particular clinical features and use of screening tools allow for a more timely and accurate detection of the disorder. There is a paucity of good quality data to guide clinicians treating BD II.<bold>Conclusion: </bold>Significant progress has been made in clarifying diagnostic and treatment issues in BD II. Neither strong nor broad treatment recommendations can be made; a cautious interpretation of available data suggests that lithium or lamotrigine are fairly reasonable first-line choices. More well-designed studies with larger samples are needed to improve the evidence base for managing this disorder.
- Subjects
AFFECTIVE disorders; EPIDEMIOLOGY; DIAGNOSIS; MEDICAL screening; THERAPEUTICS; LITHIUM; LAMOTRIGINE; DIAGNOSIS of bipolar disorder; DRUG therapy; COGNITIVE therapy; DIFFERENTIAL diagnosis; BIPOLAR disorder; PERSONALITY disorders; COMORBIDITY; DISEASE prevalence; PSYCHOLOGY
- Publication
Canadian Journal of Psychiatry, 2004, Vol 49, Issue 12, p802
- ISSN
0706-7437
- Publication type
journal article
- DOI
10.1177/070674370404901203