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- Title
Impact of an additional right pulmonary vein on second-generation cryoballoon ablation for atrial fibrillation: a propensity matched score study.
- Authors
Takarada, Ken; Ströker, Erwin; Abugattas, Juan-Pablo; de Regibus, Valentina; Coutiño, Hugo-Enrique; Lusoc, Ian; Capulzini, Lucio; Sieira, Juan; Mugnai, Giacomo; Salghetti, Francesca; Choudhury, Rajin; Iacopino, Saverio; de Asmundis, Carlo; Brugada, Pedro; Chierchia, Gian-Battista
- Abstract
<bold>Purpose: </bold>Cryoballoon (CB) technology in the context of anatomical pulmonary vein (PV) variants might hypothetically hamper successful PV isolation (PVI). Our aim was to assess the impact of a right middle PV (RMPV) in the setting of second-generation cryoballoon (CB advance-CB-A), on procedural parameters and on mid-term follow-up.<bold>Methods: </bold>Consecutive patients with AF presenting RMPV (RMPV+) at the pre-procedural computed tomography who underwent PVI by CB-A were enrolled. Comparison with propensity score-matched patients without RMPV (RMPV-) was performed. Acute procedural parameters and clinical follow-up were assessed.<bold>Results: </bold>A total of 240 patients (80 RMPV+) were included in the analysis. Twelve of 80 (15%) RMPV+ patients underwent a direct cryo-application in this variant and accomplished the isolation without phrenic nerve palsy, whereas in 25 of 80 (31%) RMPV+ patients, the RMPVs were not targeted directly nor indirectly (by co-occlusion during application at a major PV). At a median follow-up of 17.3 [interquartile range 11.3-26.5] months, there was no significant difference in AF-free survival between RMPV+ and RMPV- patients (78.8 vs 78.1%, P = 1.00), and the recurrence of atrial arrhythmias among patients with versus without an intentional or indirect cryo-application to the RMPV was not different (22 vs 20%, P = 1.00).<bold>Conclusions: </bold>Mid-term outcome after CB-A ablation did not differ between RMPV+ and RMPV- patients. Within RMPV+ patients, outcome was similar between those with versus without a cryo-application (either direct or indirect) to the additional vein.
- Subjects
PULMONARY veins; ATRIAL fibrillation; PHRENIC nerve; ATRIAL arrhythmias; COMPUTED tomography
- Publication
Journal of Interventional Cardiac Electrophysiology, 2019, Vol 54, Issue 1, p1
- ISSN
1383-875X
- Publication type
journal article
- DOI
10.1007/s10840-018-0373-8