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Liver Production of Sulfamidase Reverses Peripheral and Ameliorates CNS Pathology in Mucopolysaccharidosis IIIA Mice.
- Published in:
- Molecular Therapy, 2012, v. 20, n. 2, p. 254, doi. 10.1038/mt.2011.220
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- Publication type:
- Article
Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25697-y
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- Publication type:
- Article
Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice.
- Published in:
- Endocrinology, 2018, v. 159, n. 4, p. 1748, doi. 10.1210/en.2018-00087
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- Publication type:
- Article
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
- Published in:
- Scientific Reports, 2017, p. 43515, doi. 10.1038/srep43515
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- Publication type:
- Article
HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance.
- Published in:
- Scientific Reports, 2015, p. 14487, doi. 10.1038/srep14487
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- Publication type:
- Article
Adipose tissue is a key organ for the beneficial effects of GLP‐2 metabolic function.
- Published in:
- British Journal of Pharmacology, 2021, v. 178, n. 10, p. 2131, doi. 10.1111/bph.15278
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- Publication type:
- Article
New insights into adipose tissue VEGF-A actions in the control of obesity and insulin resistance.
- Published in:
- Adipocyte, 2013, v. 2, n. 2, p. 109, doi. 10.4161/adip.22880
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- Publication type:
- Article
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa.
- Published in:
- Cell Death & Disease, 2022, v. 13, n. 4, p. 1, doi. 10.1038/s41419-022-04839-0
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- Publication type:
- Article
Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.
- Published in:
- PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0247300
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- Publication type:
- Article
Diabetic neuropathy: Electrophysiological and morphological study of peripheral nerve degeneration and regeneration in transgenic mice that express IFNβ in β cells.
- Published in:
- Muscle & Nerve, 2010, v. 41, n. 5, p. 630, doi. 10.1002/mus.21564
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- Publication type:
- Article
Vitamin D Receptor Overexpression in β-Cells Ameliorates Diabetes in Mice.
- Published in:
- Diabetes, 2020, v. 69, n. 5, p. 927, doi. 10.2337/db19-0757
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- Publication type:
- Article
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.
- Published in:
- 2016
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- Publication type:
- journal article
In vivo adeno-associated viral vector-mediated genetic engineering of white and brown adipose tissue in adult mice.
- Published in:
- 2013
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- Publication type:
- journal article
In Vivo Adeno-Associated Viral Vector-Mediated Genetic Engineering of White and Brown Adipose Tissue in Adult Mice.
- Published in:
- Diabetes, 2013, v. 62, n. 12, p. 4012, doi. 10.2337/db13-0311
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- Publication type:
- Article
Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy.
- Published in:
- Diabetes, 2013, v. 62, n. 5, p. 1718, doi. 10.2337/db12-1113
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- Publication type:
- Article
Nonviral-Mediated Hepatic Expression of IGF-I Increases Treg Levels and Suppresses Autoimmune Diabetes in Mice.
- Published in:
- Diabetes, 2013, v. 62, n. 2, p. 551, doi. 10.2337/db11-1776
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- Publication type:
- Article
Response to Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801-1813.
- Published in:
- 2013
- By:
- Publication type:
- Letter
Vascular Endothelial Growth Factor-Mediated Islet Hypervascularization and Inflammation Contribute to Progressive Reduction of β-Cell Mass.
- Published in:
- Diabetes, 2012, v. 61, n. 11, p. 2851, doi. 10.2337/db12-0134
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- Publication type:
- Article
Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance.
- Published in:
- Diabetes, 2012, v. 61, n. 7, p. 1801, doi. 10.2337/db11-0832
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- Publication type:
- Article
Overexpression of Kinase-Negative Protein Kinase Cδ in Pancreatic β-Cells Protects Mice From Diet-Induced Glucose Intolerance and β-Cell Dysfunction.
- Published in:
- Diabetes, 2010, v. 59, n. 1, p. 119, doi. 10.2337/db09-0512
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- Publication type:
- Article
Skeletal Muscle Overexpression of Interleukin-6 Leads to Reduced Body Weight Combined with Inappropriate Hyperinsulinemia and Low Glucose Levels.
- Published in:
- Diabetes, 2007, v. 56, p. A458
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- Publication type:
- Article
Increased Glucose Uptake by Adipose Tissue Expression of Glucokinase in Transgenic Mice Leads to Lactate Production Rather than Fat Accumulation.
- Published in:
- Diabetes, 2007, v. 56, p. A458
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- Publication type:
- Article
Ped/pea-15 Regulates Glucose-Induced Insulin Secretion by Restraining Potassium Channel Expression in Pancreatic Beta-Cells.
- Published in:
- Diabetes, 2007, v. 56, p. A444
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- Publication type:
- Article
Endocrine Pancreas Regeneration in Diabetic IGF-I Transgenic Mice Results from Replication of Pre-Existing β-Cells Rather than from Bone Marrow Cell Recruitment and Differentiation.
- Published in:
- Diabetes, 2007, v. 56, p. A424
- By:
- Publication type:
- Article
Increased Intraocular IGF-I Induces Blood-Retinal Barrier Breakdown in a Transgenic Animal Model of Diabetic Retinopathy.
- Published in:
- Diabetes, 2007, v. 56, p. A26
- By:
- Publication type:
- Article
PED/PEA-15 Regulates Glucose-Induced Insulin Secretion by Restraining Potassium Channel Expression in Pancreatic β-Cells.
- Published in:
- Diabetes, 2007, v. 56, n. 3, p. 622, doi. 10.2337/db06-1260
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- Publication type:
- Article
Expression of IGF-I in Pancreatic Islets Prevents Lymphocytic Infiltration and Protects Mice From Type 1 Diabetes.
- Published in:
- Diabetes, 2006, v. 55, n. 12, p. 3246, doi. 10.2337/db06-0328
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- Publication type:
- Article
Reversal of Type 1 Diabetes by Engineering a Glucose Sensor in Skeletal Muscle.
- Published in:
- Diabetes, 2006, v. 55, n. 6, p. 1546, doi. 10.2337/db05-1615
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- Publication type:
- Article
Adipose Overexpression of Phosphoenolpyruvate Carboxykinase Leads to High Susceptibility to Diet-Induced Insulin Resistance and Obesity.
- Published in:
- Diabetes, 2006, v. 55, n. 2, p. 273, doi. 10.2337/diabetes.55.02.06.db05-0482
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- Publication type:
- Article
Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: insights from transgenic mice.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003166
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- Publication type:
- Article
Phosphofructo-1-Kinase Deficiency Leads to a Severe Cardiac and Hematological Disorder in Addition to Skeletal Muscle Glycogenosis.
- Published in:
- PLoS Genetics, 2009, v. 5, n. 8, p. 1, doi. 10.1371/journal.pgen.1000615
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- Publication type:
- Article
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
- Published in:
- JBMR Plus, 2020, v. 4, n. 1, p. 1, doi. 10.1002/jbm4.10247
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- Publication type:
- Article
In vivo Gene Transfer to Healthy and Diabetic Canine Pancreas.
- Published in:
- Molecular Therapy, 2006, v. 13, n. 4, p. 747, doi. 10.1016/j.ymthe.2005.10.017
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- Publication type:
- Article
1070. Easy Search on Clinical Gene Transfer: The Euregenethy (EC-DG Research FP5-TN) Data Base on Pre-Clinical & Clinical Gene Transfer & Therapy
- Published in:
- 2005
- By:
- Publication type:
- Abstract
901. Recovery from Type 1 Diabetes by Insulin and Glucokinase Expression in Skeletal Muscle
- Published in:
- 2005
- By:
- Publication type:
- Abstract
248. A Mouse Model of Type VII Glycogenosis to Assay Gene Therapy Approaches
- Published in:
- 2005
- By:
- Publication type:
- Abstract
236. Bone Marrow-Derived Cells Do Not Contribute to Endocrine Pancreas Regeneration in Diabetic RIP/IGF-I Transgenic Mice
- Published in:
- 2005
- By:
- Publication type:
- Abstract
Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging.
- Published in:
- Journal of Cell Biology, 2020, v. 219, n. 10, p. 1, doi. 10.1083/jcb.202002120
- By:
- Publication type:
- Article
Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34391-6
- By:
- Publication type:
- Article
Insulin inhibits liver expression of the CCAAT/enhancer-binding protein beta.
- Published in:
- 1995
- By:
- Publication type:
- journal article
Activation by vanadate of glycolysis in hepatocytes from diabetic rats.
- Published in:
- 1991
- By:
- Publication type:
- journal article
Control of glycogen synthase and phosphorylase in hepatocytes from diabetic rats. Effects of glucagon, vasopressin, and vanadate.
- Published in:
- 1989
- By:
- Publication type:
- journal article
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
- Published in:
- PLoS Genetics, 2018, v. 14, n. 8, p. 1, doi. 10.1371/journal.pgen.1007562
- By:
- Publication type:
- Article
Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.
- Published in:
- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145116
- By:
- Publication type:
- Article
Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041511
- By:
- Publication type:
- Article
Protein Kinase C Delta (PKCδ) Affects Proliferation of Insulin-Secreting Cells by Promoting Nuclear Extrusion of the Cell Cycle Inhibitor p21<sup>Cip1/WAF1</sup>.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028828
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- Publication type:
- Article
Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats.
- Published in:
- PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008771
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- Publication type:
- Article
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
- Published in:
- BMC Biology, 2023, p. 1, doi. 10.1186/s12915-022-01475-0
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- Publication type:
- Article