We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Central sensitization in adolescents with generalized hypermobility spectrum disorder or hypermobile ehlers-danlos syndrome -A feasibility study.
- Authors
Schubert-Hjalmarsson, E.; Fasth, A.; Ickmans, K.; Mårdbrink, E. L.; Söderpalm, A. C.; Lundberg, M.
- Abstract
Introduction: Pain is a major symptom in adolescents with generalized Hypermobility Spectrum Disorder (HSD) or Hypermobile Ehlers-Danlos Syndrome (hEDS) (1). Central sensitization (CS) of pain has been suggested as a possible explanation (2). The aim of this study was to investigate the feasibility of a study protocol investigating features of CS in adolescents with HSD or hEDS for further studies. Introduction: Pain is a major symptom in adolescents with generalized Hypermobility Spectrum Disorder (HSD) or Hypermobile Ehlers-Danlos Syndrome (hEDS) (1). Central sensitization (CS) of pain has been suggested as a possible explanation (2). The aim of this study was to investigate the feasibility of a study protocol investigating features of CS in adolescents with HSD or hEDS for further studies. Results: All three measurements were well tolerated by all participants (patients and control). When measuring endogenous pain modulation through CPM, there were five participants (patients and control), who did not experience pain when immersing their hand in the cold water and as such a CPM reaction was not achieved. Discussion: The test protocols proved to have a good feasibility but there is a need to adapt the protocol to obtain more reliable data in the main study. For example, reduction of the water sample temperature. Process evaluation: One suggestion for improving the study is to add additional measurements for example time required for examinations, time required for completing the questionnaire.
- Subjects
NETHERLANDS; EHLERS-Danlos syndrome; PAIN; CONFERENCES &; conventions; CENTRAL nervous system
- Publication
Pain Practice, 2022, Vol 22, p20
- ISSN
1530-7085
- Publication type
Article
- DOI
10.1111/papr.13128