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- Title
2019 年至 2022 年儿童呼吸道感染病原菌分布特征和耐药分析.
- Authors
张学林; 刘 璐; 陈艳芝; 查才军; 李艳丽
- Abstract
Objective To analyze the clinical characteristics and the antimicrobial resistance of respiratory tract infection in children in Baoshan City, guide clinicians to rationally apply antibiotics, and improve the success rate of treatment. Methods Retrospective analysis of the distribution characteristics and drug sensitivity results of 1 039 strains of pathogens detected in pediatric inpatients of hospitals from 2019 to 2022 was conducted. Results The main pathogens causing the respiratory infections in children in Baoshan area were Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus, Haemophilus influenzae, Klebsiella pneumoniae and Pseudomonas aeruginosa.Analysis of the drug sensitivity results of pathogenic bacteria with a detected quantity greater than 80 revealed that Streptococcus pneumoniae had a high resistance rate to erythromycin, clindamycin, and compound sulfamethoxazole. The resistance rates of penicillin, ceftriaxone, cefotaxime, and meropenem were P<0.05, and the difference was statistically significan. Methicillin-resistant Staphylococcus aureus (MRSA) was11.1%;CTX/CRO-R-ECO, CTX/CRO-R-KPN, CR-ECO and CR-KPN were lower than the 2021 ISPED level;The P.aeruginosa drug resistance rate and H.influenzae’s ampicillin and ampicillin/sulbactam were higher than the 2021 ISPED level. Conclusion The treatment of respiratory tract infections in pediatric patients faces great challenges.The non-standard use of empirical medication has led to the emergence of multidrug-resistant bacteria, and the selection of anti infection treatment drugs is limited. Therefore, it is imperative to grasp the epidemic characteristics and drug resistance of pathogenic bacteria in the local area.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2024, Vol 45, Issue 1, p149
- ISSN
2095-610X
- Publication type
Article
- DOI
10.12259/j.issn.2095-610X.S20240125