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- Title
Regional variations in the relative sensitivity to UV light in the mouse retina.
- Authors
Calderone, Jack B.; Jacobs, Gerald H.
- Abstract
About 3% of all mouse photoreceptors are cones. An earlier electrophysiological study indicated that there were two classes of cone in the mouse retina having peak sensitivities (λmax) of about 360 nm and 511 nm. Recent immunocytochemical results show there are two types of cones that have distinctive regional segregation patterns. We used regional stimulation of the retina in conjunction with electroretinogram (ERG) flicker photometry to see if the two cone types identified electrophysiologically are regionalized in a fashion suggested by the anatomical results. We find they are. Relative sensitivity to ultraviolet and visible light stimulation qualitatively parallels that predicted by immunocytochemical labelling. One result of this remarkable regionalization of cone types is that the mouse retina is relatively more sensitive to ultraviolet light stimulation when that light is directed toward the ventral half of the retina.
- Publication
Visual Neuroscience, 1995, Vol 12, Issue 3, p463
- ISSN
0952-5238
- Publication type
Article
- DOI
10.1017/S0952523800008361