We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Isolated oculomotor nerve palsy as a paraneoplastic manifestation of gastric diffuse large B-cell lymphoma: A case report.
- Authors
SHANG-YIH YAN; YI-JEN PENG; CHUN-SHU LIN; GIIA-SHEUN PENG; PING-YING CHANG
- Abstract
Isolated oculomotor nerve palsy (ONP) is rare. The major causes are aneurysm of the posterior communicating artery, microvascular ischemia, neoplasm, inflammation and trauma. The present study reports the case of a 72-year-old female with left isolated pupil-sparing ONP and severe anemia as the initial manifestations of gastric diffuse large B-cell lymphoma (DLBCL). Systemic chemotherapy without any central nervous system (CNS)-directed treatment led to a complete resolution of the ONP, suggesting that it was most likely to be a paraneoplastic phenomenon. If CNS involvement cannot be demonstrated by brain magnetic resonance imaging and cerebrospinal fluid assessment, the present case suggests that it may be acceptable to omit CNS-directed therapy in such cases of ONP, since it may be paraneoplastic in nature and may resolve following successful treatment of the underlying malignancy.
- Subjects
OCULOMOTOR nerve; CEREBRAL palsy
- Publication
Oncology Letters, 2014, Vol 8, Issue 5, p1983
- ISSN
1792-1074
- Publication type
Case Study
- DOI
10.3892/ol.2014.2454