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- Title
Erythroderma, an unusual manifestation of B cell lymphoma.
- Authors
eong, A. S. Y.; Cowled, P. A.; Zalewski, P. D.; Burrys, J. N.; Meredith, D. J.; Forbes, I. J.
- Abstract
A case is described in which the initial manifestation of a malignant lymphoma was an erythematous skin rash over the face, scalp and trunk. Immunological surface marker analysis showed the malignant cells to be of B lymphocyte origin with a homogeneous secretion of IgM-K. Repeated skin and lymph node biopsies and finally post mortem documented the progression of the lymphoma from that of a mixed lymphocytic-histiocytic type with a nodular pattern of growth to a diffuse histiocytic lymphoma with frequently bizarre cells. The theory of ecotaxis or homing of lymphocytes to the skin and other non-lymphoid organs of the body is discussed in an attempt to explain the occurrence of cutaneous involvement as a primary manifestation of lymphoma.
- Subjects
ERYTHEMA; LYMPHOMAS; B cells; CELLS; BIOPSY; SKIN
- Publication
British Journal of Dermatology, 1978, Vol 99, Issue 1, p99
- ISSN
0007-0963
- Publication type
Article