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- Title
Prenatal diagnosis of β-thalassaemia using fetal erythroblasts enriched from maternal blood by a novel gradient.
- Authors
Di Naro, Edoardo
- Abstract
Assesses the novel technique for the isolation of fetal erythroblasts from maternal blood for the non-invasive prenatal diagnosis of pregnancies at risk of beta-thalassaemia. Autosomal recessive single gene disorders; Erythroblasts separation through gradient and high speed centrifugation; Immunohistochemical identification of erythroblasts; Use of single cell polymerase chain reaction; Diagnosis of fetal hemoglobinopathies.
- Subjects
THALASSEMIA diagnosis; DIAGNOSIS of fetal diseases; BLOOD cells
- Publication
Molecular Human Reproduction, 2000, Vol 6, Issue 6
- ISSN
1360-9947
- Publication type
Article
- DOI
10.1093/molehr/6.6.571