We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sulfated Polysaccharides from Tunisian Fish Skins: Antioxidant, DNA Damage Protective Effect and Antihypertensive Activities.
- Authors
Krichen, Fatma; Karaoud, Wafa; Sayari, Nadhem; Sila, Assaâd; Kallel, Fatma; Ellouz-Chaabouni, Semia; Bougatef, Ali
- Abstract
Sulfated polysaccharides were isolated from two Tunisian fish skins grey triggerfish ( Balistes capriscus) (GTSP) and smooth hound ( Mustelus mustelus) (SHSP). Their chemical and physical characteristics were investigated. The Analysis of surface morphology by scanning electron microscopy of both sulfated polysaccharides displayed the same shape with netted structure. The antioxidant activities of GTSP and SHSP were evaluated using various in vitro antioxidant assays: 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, reducing power, β-carotene bleaching inhibition assay (IC = 0.5 mg mL and IC = 0.6 mg mL) and DNA nicking assay. Both sulfated polysaccharides exhibited good antioxidant activities. The sulfated polysaccharides showed strong angiotensin I-converting enzyme inhibitory activities (IC = 0.16 mg mL and IC = 0.18 mg mL). These results revealed that GTSP and SHSP exhibited significant antihypertensive activities. Overall, the results indicated that grey triggerfish and smooth hound skins can be used to generate high value-added products, thus offering a valuable source of bioactive sulfated polysaccharides for application in wide range of biotechnological applications.
- Subjects
POLYSACCHARIDES; SURFACE morphology; BALISTIDAE; CAROTENES
- Publication
Journal of Polymers & the Environment, 2016, Vol 24, Issue 2, p166
- ISSN
1566-2543
- Publication type
Article
- DOI
10.1007/s10924-016-0759-6