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- Title
Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn.
- Authors
Sireeratawong, Seewaboon; Itharat, Arunporn; Lerdvuthisopon, Nusiri; Piyabhan, Pritsana; Khonsung, Parirat; Boonraeng, Supot; Jaijoy, Kanjana
- Abstract
Piper interruptum Opiz. and Piper chaba Linn. are herbaceous plants in the Piperaceae family. The ethanol extract of P. interruptum and P. chaba inhibited ethyl phenylpropiolate-induced ear edema and carrageenan-induced hind paw edema in rats. Both extracts reduced transudative and granuloma weights as well as body weight gain and thymus weight of the chronic inflammatory model using cotton pellet-induced granuloma formation in rats. Moreover, both extracts exhibited analgesic activity on both early phase and late phase of formalin test in mice and also showed antipyretic activity on yeast-induced hyperthermia in rats
- Subjects
HERBACEOUS plants; ANTI-inflammatory agents; ANTIPYRETICS; ETHANOL; PIPERACEAE; GRANULOMA; LABORATORY rats
- Publication
ISRN Pharmacology, 2012, p1
- ISSN
2090-5165
- Publication type
Article
- DOI
10.5402/2012/480265