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- Title
Prevalence of Invasive Aspergillosis Among (PTB) Patients in Kanchipuram, India.
- Authors
SIVASANKARI S.; SENTHAMARAI S.; ANITHA C.; SASTRY, APURBA SANKAR; BHATT, SANDHYA; KUMUDHAVATHI M. S.; AMSHAVATHANI S. K.
- Abstract
Background: Tuberculosis (TB) remains a major health problem worldwide. (PTB) is commonly associated with secondary aspergilloma. Repeated exposure of Aspergillus spores can aggravate the bronchial pathology and can manifest as asthmatic episodes. Aim and Objective: Pulmonary invasive aspergillosis is difficult to evaluate. Culture based diagnosis is time consuming. Hence (PCR) was done to evaluate the invasive fungal aspergillosis in (PTB) patients. Materials and Methods: Eighty sputum samples collected from TB patients were processed as per standard protocol. Species level identification was done using PCR. Results: Among 80 patients, 26 isolates were obtained, only 8 were Aspergillus species. All Aspergillus were taken up for PCR evaluation. Conclusion: Fungal infection should be suspected in all sputum positive patients. PCR is an effective tool to diagnose invasive aspergillosis.
- Subjects
ASPERGILLOSIS; ASPERGILLOSIS treatment; TUBERCULOSIS diagnosis; TUBERCULOSIS patients; TUBERCULOSIS treatment; PATIENTS
- Publication
Journal of Clinical & Diagnostic Research, 2014, Vol 8, Issue 3, p22
- ISSN
0973-709X
- Publication type
Article
- DOI
10.7860/JCDR/2014/7957.4094