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- Title
A facile and efficient synthesis of 1-trichloromethyl-1,2-dihydrobenzo[ b][1,6]naphthyridines via three-component reaction among 2-alkynylquinoline-3-carbaldehydes, primary amines, and chloroform.
- Authors
Bukšnaitienė, Rita; Čikotienė, Inga
- Abstract
A three-component reaction among 2-alkynylquinoline-3-carbaldehydes, primary amines, and chloroform leading to novel 1-(trichloromethyl)-1,2-dihydrobenzo[ b][1,6]naphthyridines was developed using microwave initiation in an absence of any catalysts. This method provides a facile approach to the title compounds with moderate to higher yields.
- Subjects
HETEROCYCLIC compounds synthesis; TRICHLOROMETHYL group; CHLOROFORM; AMINES; NAPHTHYRIDINES; CHEMICAL reactions
- Publication
Heterocyclic Communications, 2012, Vol 18, Issue 2, p87
- ISSN
0793-0283
- Publication type
Article
- DOI
10.1515/hc-2011-0106