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- Title
1,2-Ethanedithiol-induced Erythema Multiforme-like Contact Dermatitis.
- Authors
Jeng-Wei Tjiu; Chia-Yu Chu; Chee-Ching Sun
- Abstract
Contact dermatitis simulating erythema multiforme can be caused by many allergens. The chemical agent 1,2-ethanedithiol, which serves as a protective group in chemical synthesis, has hitherto only been implicated as an irritant. We report on a 22-year-old female chemistry student who developed widespread erythema multiforme-like lesions after local contact with 1,2-ethanedithiol. Many target lesions were observed bilaterally on her hands, forearms, arms, and on her forehead. One such lesion was histologically compatible with erythema multiforme. The patient had a positive patch test to 1,2-ethanedithiol, whereas none of 30 healthy subjects showed a positive reaction. However, eight of the 30 controls (26.7%) developed irritant reactions to 1,2-ethanedithiol. Cautious handling of the compound is a prudent precaution.
- Subjects
ERYTHEMA multiforme; CONTACT dermatitis; DELAYED hypersensitivity; SKIN inflammation; SKIN diseases; DERMATOLOGY
- Publication
Acta Dermato-Venereologica, 2004, Vol 84, Issue 5, p393
- ISSN
0001-5555
- Publication type
Article
- DOI
10.1080/00015550410033571