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- Title
Paroxysmal nocturnal haemoglobinuria clones in children with acquired aplastic anaemia: a prospective single centre study.
- Authors
Timeus, Fabio; Crescenzio, Nicoletta; Lorenzati, Anna; Doria, Alessandra; Foglia, Luiselda; Pagliano, Sara; Quarello, Paola; Ramenghi, Ugo; Saracco, Paola
- Abstract
The article focuses on the study related to the incidence of paroxysmal nocturnal haemoglobinuria (PNH) in children with aplastic anemia (AA). The current study indicates that the incidence of minor PNH clones in the AA children at diagnosis matches the reports of similar study conducted on adults and draws the conclusion that the screening for PNH clones along with other assessments may help provide information regarding bone marrow disease in children with AA.
- Subjects
APLASTIC anemia; PAROXYSMAL hemoglobinuria; CHILDREN; IMMUNOSUPPRESSIVE agents; DIAGNOSIS; BONE marrow diseases
- Publication
British Journal of Haematology, 2010, Vol 150, Issue 4, p483
- ISSN
0007-1048
- Publication type
Letter
- DOI
10.1111/j.1365-2141.2010.08219.x