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- Title
Synthesis and Biological Evaluation of Curcumin Analogs as Antiplatelet Inhibitor.
- Authors
Dong Won Lee; Jin Hun Park; Seung Soo Yoon
- Abstract
The article provides information on a study which examined extensive structure-activity relationships (SAR) of the synthesized curcumin compounds to obtain better pharmacological profiles with in vitro activity. Topics discussed include the relationship between curcumin-derived pyrazoles of the 1,3-dicarbonyl with hydrazines and curcumin-ester of the phenol position and purification of curcumin and bisdemethoxycurcumin from commercial curcuminoids.
- Subjects
STRUCTURE-activity relationships; CURCUMIN; PHARMACOLOGY; PYRAZOLES; CARBONYL compounds; HYDRAZINES
- Publication
Bulletin of the Korean Chemical Society, 2014, Vol 35, Issue 5, p1537
- ISSN
0253-2964
- Publication type
Article
- DOI
10.5012/bkcs.2014.35.5.1537