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- Title
Physicochemical Investigation of Paracetamol – Caffeine Solid Mixtures.
- Authors
Tkachenko, M. L.; Zhnyakina, L. E.; Kosmynin, A. S.
- Abstract
Investigates the phase equilibria in a caffeine-paracetamol system, in which both components are characterized by low solubility. Mutual influence of components on their solubility and the release from certain particular compositions; Phase diagram of the caffeine-paracetamol system; Differential thermal analysis; Anomalous increase in the dissolution rate and solubility of both components.
- Subjects
PHARMACEUTICAL industry; PHASE diagrams; PHASE equilibrium; CAFFEINE; ACETAMINOPHEN; ANALGESICS; SOLUBILITY
- Publication
Pharmaceutical Chemistry Journal, 2003, Vol 37, Issue 8, p430
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1023/A:1027312131095