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- Title
Efficacy of antibiotic prophylaxis for the prevention of Lyme disease: an updated systematic review and meta-analysis.
- Authors
Warshafsky, Stephen; Lee, David H.; Francois, Louise K.; Nowakowski, John; Nadelman, Robert B.; Wormser, Gary P.
- Abstract
Background: The clinical value of antibiotic prophylaxis in preventing Lyme disease remains uncertain, owing to a meta-analysis lacking sufficient power to demonstrate efficacy and a more recent trial showing effectiveness but lacking precision. Our objective was to update our prior meta-analysis on antibiotic prophylaxis for the prevention of Lyme disease, to obtain a more precise estimate of treatment effect.
- Subjects
ANTIBIOTICS; DRUG efficacy; LYME disease treatment; BORRELIA burgdorferi; PRIMARY care; MICROBIAL metabolites
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2010, Vol 65, Issue 6, p1137
- ISSN
0305-7453
- Publication type
Article
- DOI
10.1093/jac/dkq097