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- Title
Two new gene cassettes, dfr17 (for trimethoprim resistance) and aadA4 (for spectinomycin/streptomycin resistance), inserted in an Escherichia coli class 1 integron.
- Authors
Chang, Chung-Yu; Chang, Lin-Li; Chang, Yu-Hung; Lee, Tsong-Ming; Li, Yuan-Hung; Chang, Shui-Feng; Chang, C Y; Chang, L L; Chang, Y H; Lee, T M; Li, Y H; Chang, S F
- Abstract
Two new gene cassettes, dfr17 and aadA4, inserted in a class 1 integron of Escherichia coli EC107, are described here. The dfr17 cassette encodes trimethoprim resistance and has 91% identity with the dfrVII dihydrofolate reductase gene. The aadA4 cassette confers resistance to spectinomycin and streptomycin and shows 94% identity with the aadA3 gene. The integron carrying the dfr17 and aadA4 cassettes was located on a conjugative plasmid, pEC1072.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2000, Vol 46, Issue 1, p87
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/46.1.87