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- Title
GSOAP: a tool for visualization of gene set over-representation analysis.
- Authors
Tokar, Tomas; Pastrello, Chiara; Jurisica, Igor
- Abstract
Motivation Gene sets over-representation analysis (GSOA) is a common technique of enrichment analysis that measures the overlap between a gene set and selected instances (e.g. pathways). Despite its popularity, there is currently no established standard for visualization of GSOA results. Results Here, we propose a visual exploration of the GSOA results by showing the relationships among the enriched instances, while highlighting important instance attributes, such as significance, closeness (centrality) and clustering. Availability and implementation GSOAP is implemented as an R package and is available at https://github.com/tomastokar/gsoap.
- Subjects
VISUALIZATION; GENES; CENTRALITY; POPULARITY
- Publication
Bioinformatics, 2020, Vol 36, Issue 9, p2923
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btaa001