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- Title
The Prevalence of Cases of B-Thalassemia Minor Among the Hematologically Suspected Cases in Kerbala.
- Authors
Hassan, Duha Maitham; Ali, Mohammed Shnain
- Abstract
Background: B-thalassemia minor is the symptomless carrier state of B-thalassemia that can be misdiagnosed as mild iron deficiency anemia (IDA). Aim: This work aims to assess the prevalence of cases of B-thalassemia minor among the suspected cases and to compare the results of diagnosis depending on single confirmatory test (Hb electrophoresis) and three confirmatory tests (reticulocyte count, serum ferritin and Hb electrophoresis). Materials and methods: In this study 50 cases of mild anemia (Hb =9-11.99 g/dl) with initial hematological suspicion of B-thalassemia minor were studied for detailed confirmatory diagnostic tests that include reticulocyte count, Hb electrophoresis for HbA2 estimation and S.Ferritin level. Results: Results showed that 43/50 i.e 86% of suspected cases are confirmed by three tests (41/50 i.e (82%) have B-thalassemia minor, 2/50 i.e (4%) have B-thalassemia minor and IDA), 6/50 i.e (12%) have iron deficiency anemia (IDA), while 1/50 i.e (2%) have polycythemia (on venesections). Discussion: Results showed that 86% of initially suspected cases are confirmed to have Bthalassemia minor and 4% of cases have B-thalassemia minor with IDA depending on three tests for confirmatory diagnosis which are reticulocytosis, HbA2 concentration and S.Ferritin level. Similar results were encountered by Cristina Passarello, Antonino Giambona, et al. Conclusion: The prevalence of cases of B-thalassemia minor among the hematological suspected cases in Kerbala is 86%.
- Subjects
THALASSEMIA; IRON deficiency anemia; DISEASE prevalence; ELECTROPHORESIS; POLYCYTHEMIA
- Publication
Kerbala Jorunal of Medicine, 2017, Vol 10, Issue 3, p3841
- ISSN
1990-5483
- Publication type
Article