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- Title
A case for the use of chemotherapy in hereditary mitochondrial optic neuropathies: Successful administration of cisplatin/etoposide in a male patient with testicular seminoma and Leber's hereditary optic neuropathy.
- Authors
Vrisakis, Jean‐Luc; Fraser, Clare L.; Shahnam, Adel; Nindra, Udit; Grimison, Peter
- Abstract
Key Clinical Message: We report on the successful use of chemotherapy for treatment of stage 2B testicular seminoma in a carrier of the Leber's hereditary optic neuropathy 11778 mitochondrial mutation. Neurotoxic chemotherapy may not prompt disease conversion.
- Subjects
LEBER'S hereditary optic atrophy; SEMINOMA; CISPLATIN; MITOCHONDRIA; CANCER chemotherapy; NEUROPATHY; ETOPOSIDE
- Publication
Clinical Case Reports, 2024, Vol 12, Issue 7, p1
- ISSN
2050-0904
- Publication type
Case Study
- DOI
10.1002/ccr3.9045