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- Title
Evaluation of Anaphylaxis Patients Applying to the Emergency Department.
- Authors
AZCAN, Sevdenur; TAŞLIDERE, Bahadır
- Abstract
Introduction: Anaphylaxis is a potentially life-threatening systemic hypersensitivity reaction requiring prompt treatment. Our study evaluated anaphylaxis cases in the emergency department to raise awareness and guide management. Method: Our study was conducted at Bezmialem Vakıf University, Faculty of Medicine Hospital from January 01, 2018, to December 31, 2022. The study focused on patients aged 18 years and above. Anaphylaxis diagnosis followed the National Institute of Allergy and Infectious Disease 2021 guidelines. The initial treatment involved intramuscular adrenaline, with infusion therapy for unresponsive cases. Patient data were recorded for demographics, comorbidities, consciousness, and examination findings. Results: In a total of 77 evaluated patients, 54.4% were female and 45.6% were male. Reasons for adrenaline administration included unknown causes (51.5% intramuscular, 44.4% infusion). Overall, 49.4% had unknown triggers and 15.6% attributed reactions to medication. Food and insect stings were followed in sequence (p=0.03). Dermatological complaints were noted in 13% (p<0.001). Comorbidities were present in 36.8% (intramuscular) and 88.9% (infusion), totaling 42.9% (p=0.004). Epinephrine was administered within the first hour in 76.5% (intramuscular) and 55.6% (infusion), totaling 74% (p=0.01). Bifasic reactions occurred in 8.8% (intramuscular, p=0.004). Eight patients (10.4%) required intensive care, with 66.7% in the infusion group (p<0.01). One patient died, resulting in a 1.3% mortality rate. Conclusion: If initial intramuscular injections are insufficient, initiating infusion therapy is recommended for a more stable response, particularly in patients with neurological symptoms. Monitoring comorbidities is crucial because of their increased anaphylaxis risk. The absence of biphasic reactions in patients receiving infusion therapy is important for disease monitoring.
- Subjects
ANAPHYLAXIS; HOSPITAL emergency services; INFUSION therapy; CONSCIOUSNESS raising; INTRAMUSCULAR injections
- Publication
Bezmialem Science, 2024, Vol 13, pS40
- ISSN
2148-2373
- Publication type
Article