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- Title
Evaluation of Medical and Economical Efficacy of Some Protocols for Treatment of Postpartum Clinical Endometritis in Holstein Dairy Cows.
- Authors
Khalil, Hossam M.; Waheeb, Reham S.; Abd El-Rheem, Samia M.; El-Amrawi, Gamal A.
- Abstract
Endometritis is one of the most common postpartum diseases which affect dairy cows. The disease is caused by bacterial invasion causing severe economic losses that include treatment costs, declined reproductive performance, and decreased milk yield. This study was conducted to evaluate the efficacy and economic profitability of some treatment protocols of endometritis. Forty cycling parturient Holstein dairy cows diagnosed with clinical endometritis were divided equally and treated as follow: Group 1: received PGF2α (500μg Cloprostenol, Ovu-prost®). Group 2: received PGF2α + 500mg cephapirin (Metricure®) by intrauterine infusion, (group 1 and 2 had CL on their ovaries). Group 3: cows were treated with Metricure® only. Group 4: received 100 ml of Lugol's Iodine solution (0.5%) by intra-uterine infusion (group 3 and 4 without CL on their ovaries).The results showed that animals received PGF2α+cephapirin recorded less days from treatment to recovery, shorter days open, and highest conception rate when compared to other groups. Hematological findings at day 10 post-treatment showed that all the therapeutic protocols significantly decreased total leukocytic count except treatment protocol of Group-1. All of the groups showed significant increase in eosinophils%. Also, all the treated groups recorded significant decrease in serum level of C-reactive protein (CRP) and inteleukin-6 (IL-6) compared to its level before treatment. Additionally, treatment protocol of Group-2 presented the best values in terms of economical aspect. In conclusion, cephapirin is potentially recommended for treatment of clinical endometritis in cows, PGF2α could be combined if CL was detected.
- Subjects
DAIRY cattle; ENDOMETRITIS; MEDICAL protocols; MILK yield; PUERPERIUM; LACTATION in cattle
- Publication
Alexandria Journal of Veterinary Sciences, 2023, Vol 79, Issue 1, p150
- ISSN
1110-2047
- Publication type
Article
- DOI
10.5455/ajvs.157185