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- Title
A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing.
- Authors
Lin-feng Li
- Abstract
Background: The prevalence of sensitization to cocamidopropyl betaine (CAPB) in China has not been reported. Objective: This study is to evaluate the prevalence of CAPB sensitization in patients patch tested in Peking University Third Hospital, Beijing. Methods: 429 consecutive patients with suspected allergic contact dermatitis were patch tested with CAPB 1.0% aqueous, 3-dimethylaminopropylamine (DMAPA) 1.0% aqueous as well as a modified European standard series of allergens from June 2005 to August 2006. Results: 42 patients (9.8%) had a positive reaction to CAPB. 25 of them (59.5%) were considered relevant. Of those, 7 were head and/or neck dermatitis, 4 hand dermatitis, 1 cheilitis, and the other 13 patients were widespread dermatitis. 10 out of 429 (2.3%) patients reacted to DMAPA. Of those, 8 were relevant and 6 of them also reacted to CAPB. Conclusion: The rate of CAPB sensitization in our study is higher than previously reported elsewhere. CAPB is a common cosmetic allergen in Beijing. Both CAPB and DMAPA should be tested in patients with suspected cosmetic dermatitis.
- Subjects
MEDICAL research; SKIN inflammation; ALLERGENS; TRANSFER factor (Immunology); PATIENTS
- Publication
Contact Dermatitis (01051873), 2008, Vol 58, Issue 1, p24
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.2007.01251.x