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- Title
Focal Uptake in the Sternum on 18 F-FDG-PET/CT Caused by G-CSF Therapy after Chemotherapy Mimicking Bone Metastasis of Breast Cancer.
- Authors
Hayashi, Kumiko; Fujioka, Tomoyuki; Hara, Masatake; Kumaki, Yuichi; Oda, Goshi; Yamaga, Emi; Mori, Mio; Ohnishi, Iichiroh; Kubota, Kazunori; Nakagawa, Tsuyoshi
- Abstract
A woman in her 70s was diagnosed with left breast cancer and left axillary lymph node metastasis by an ultrasound-guided biopsy. 18F-FDG-PET/CT showed strong FDG accumulation in the tumor in the left breast and a left axillary lymph node. Neoadjuvant chemotherapy (NAC) was administered in combination with a G-CSF injection to prevent febrile neutropenia. The post-treatment 18F-FDG-PET/CT showed the disappearance of the left breast tumor and left axillary lymph node and revealed a solitary new area of strong FDG accumulation in the sternum. To rule out the possibility of sternal metastasis, a sternal biopsy was performed at the same time as surgery, which revealed no malignant findings. Although very rare, focal uptake on 18F-FDG-PET/CT performed after anticancer drug therapy with G-CSF may mimic a solitary bone metastasis. A bone biopsy may be a useful technique to avoid an immediate misdiagnosis of bone metastasis.
- Subjects
METASTATIC breast cancer; SENTINEL lymph node biopsy; BONE metastasis; STERNUM; GRANULOCYTE-colony stimulating factor; LYMPHATIC metastasis; FEBRILE neutropenia
- Publication
Diagnostics (2075-4418), 2022, Vol 12, Issue 10, p2308
- ISSN
2075-4418
- Publication type
Article
- DOI
10.3390/diagnostics12102308