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- Title
Impacto del sexo en los tiempos de cateterismo y en el uso de pretratamiento antiagregante plaquetario en pacientes con síndrome coronario agudo sin elevación del segmento ST (SCASEST).
- Authors
Martínez-Guisado, Antonio; Cepas-Guillén, Pedro; Díez-Villanueva, Pablo; López Lluva, María Thiscal; Jurado-Román, Alfonso; Bazal-Chacón, Pablo; Negreira-Caamaño, Martín; Olavarri-Miguel, Iván; Elorriaga, Ane; Rivera-López, Ricardo; Escribano, David; Salinas, Pablo; Vaquero-Luna, Jessica; Prieto, Alicia; Pérez-Cebey, Lucía; Carrasquer, Anna; Llaó, Isaac; Torres Mezcúa, Fernando José; Giralt-Borrell, Teresa; Matute-Blanco, Lucía
- Abstract
Objective. To assess differences in the clinical management of nonST-segment elevation myocardial infarction (NSTEMI), including in-hospital events, according to biological sex. Methods. Prospective observational multicenter study of patients diagnosed with NSTEMI and atherosclerosis who underwent coronary angiography. Results. We enrolled 1020 patients in April and May 2022; 240 (23.5%) were women. Women were older than men on average (72.6 vs 66.5 years, P < .001), and more women were frail (17.1% vs 5.6%, P < .001). No difference was observed in pretreatment with any P2Y12 inhibitor (prescribed in 68.8% of women vs 70.2% of men, P = .67); however, more women than men were prescribed clopidogrel (56% vs 44%, P = .009). Women prescribed clopidogrel were more often under the age of 75 years and not frail. Coronary angiography was performed within 24 hours less corooften in women (29.8% vs 36.9%, P = .03) even when high risk was recognized. Frailty was independently associated with deferring coronary angiography in the adjusted analysis; biological sex by itself was not related. The frequency and type of revascularization were the same in both sexes, and there were no differences in in-hospital cardiovascular events. Conclusions. Women were more often prescribed less potent antithrombotic therapy than men. Frailty, but not sex, correlated independently with deferral of coronary angiography. However, we detected no differences in the frequency of coronary revascularization or in-hospital events according to sex.
- Subjects
NON-ST elevated myocardial infarction; MYOCARDIAL ischemia; SEX distribution; DISEASE management; HOSPITAL care; SCIENTIFIC observation; ATHEROSCLEROSIS; TREATMENT effectiveness; REVASCULARIZATION (Surgery); FIBRINOLYTIC agents; DESCRIPTIVE statistics; LONGITUDINAL method; ACUTE coronary syndrome; RESEARCH; CLOPIDOGREL; PHYSICIAN practice patterns; PERCUTANEOUS coronary intervention; COMBINED modality therapy; CORONARY angiography; DRUG prescribing; DATA analysis software; PLATELET aggregation inhibitors; DRUGS; TIME
- Publication
Emergencias, 2024, Vol 36, Issue 2, p123
- ISSN
1137-6821
- Publication type
Article
- DOI
10.55633/s3me/016.2024