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- Title
Effect of acute and chronic whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia.
- Authors
Alentorn-Geli E; Moras G; Padilla J; Fernández-Solà J; Bennett RM; Lázaro-Haro C; Pons S
- Abstract
OBJECTIVE: The purpose of this study was to investigate the effect of acute and chronic whole-body vibration exercise on serum insulin-like growth factor-1 (IGF-1) levels in women with fibromyalgia. METHODS: A randomized controlled two-factor mixed experimental design was used. Twenty-four women with fibromyalgia (age +/- standard error of the mean, 54.95 +/- 2.03) were randomized into the vibration group or the control group. The vibration group underwent a protocol of static and dynamic tasks with whole-body vibration exercise twice a week for a total of six weeks, whereas the control group performed the same protocol without vibratory stimulus. Both groups continued their usual pharmacological treatment. Serum IGF-1 levels were determined using enzyme-linked immunosorbent assay (ELISA). To test the effects of long-term whole-body vibration exercise, serum IGF-1 measurements were taken at baseline and at weeks 1, 3, and 6 of the intervention. To test the short-term effects, at week 1, serum IGF-1 measurements were taken before and immediately following a session of whole-body vibration exercise. RESULTS: Treatment adherence was 93% in the vibration group and 92% in the control group. None of the subjects dropped out of the study. There was an absence of change in IGF-1 at week 1 and week 6 of whole-body vibration exercise. CONCLUSION: Results show no change in serum IGF-1 levels in women with fibromyalgia undergoing whole-body vibration exercise. Although high-intensity exercise and whole-body vibration exercise have been shown to increase serum IGF-1 in healthy individuals, the effectiveness of whole-body vibration exercise as a strategy to produce improvements in serum IGF-1 levels in women with fibromyalgia could not be demonstrated.
- Publication
Journal of Alternative & Complementary Medicine, 2009, Vol 15, Issue 5, p573
- ISSN
1075-5535
- Publication type
Journal Article
- DOI
10.1089/acm.2008.0366