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- Title
A Rare Case of Cytomegalovirus Colitis with Subsequent Non-tubercular Mycobacteria Immune Reconstitution Inflammatory Syndrome.
- Authors
Hashmi, Syed Asif; Arora, Sumit; Khan, Inam Danish; Varghese, Jeenu; Pandey, Rahul
- Abstract
Cytomegalovirus (CMV) colitis occurs commonly in immunocompromised patients with high mortality. CMV infection has also been reported in immunocompetent individuals and it has a varied clinical presentation. When HIV-infected patients are started on antiretroviral therapy (ART) there is a reconstitution of the immune system which results in the paradoxical worsening of existing conditions or development of new disease conditions known as immune reconstitution inflammatory syndrome (IRIS). In the setting of IRIS one of the most common infections to occur is non-tubercular mycobacteria (NTM). The infection generally develops when the CD4 count is < 50 cells/µL. Here we present a rare case of CMV colitis followed by NTM infection in the setting of IRIS, its management, and treatment outcomes.
- Subjects
MYCOBACTERIAL disease diagnosis; COLITIS diagnosis; CYTOMEGALOVIRUS disease diagnosis; HIV infections; CYTOMEGALOVIRUS diseases; ANTIRETROVIRAL agents; TREATMENT effectiveness; IMMUNE reconstitution inflammatory syndrome; VALGANCICLOVIR; COLITIS; DISEASE complications
- Publication
Middle East Journal of Digestive Diseases, 2023, Vol 15, Issue 1, p63
- ISSN
2008-5230
- Publication type
Article
- DOI
10.34172/mejdd.2023.323