Works matching AU Unoki, Motoko

Results: 34

CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome.

Published in:

2019

By:

Motoko Unoki;
Hironori Funabiki;
Velasco, Guillaume;
Francastel, Claire;
Sasaki, Hiroyuki;
Unoki, Motoko;
Funabiki, Hironori

Publication type:

journal article

Exploring the intersection of epigenetics, DNA repair, and immunology from studies of ICF syndrome, an inborn error of immunity.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1405022

By:

Motoko Unoki

Publication type:

Article

Exploring the intersection of epigenetics, DNA repair, and immunology from studies of ICF syndrome, an inborn error of immunity.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1405022

By:

Unoki, Motoko

Publication type:

Article

Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.

Published in:

Cellular Microbiology, 2008, v. 10, n. 4, p. 908, doi. 10.1111/j.1462-5822.2007.01093.x

By:

Brunet, Julie;
Pfaff, Alexander W.;
Abidi, Ahmed;
Unoki, Motoko;
Nakamura, Yusuke;
Guinard, Marie;
Klein, Jean-Paul;
Candolfi, Ermanno;
Mousli, Marc

Publication type:

Article

Low awareness but high willingness to engage in science communication: a cross-disciplinary survey study in a Japanese University.

Published in:

Scientometrics, 2025, v. 130, n. 3, p. 1357, doi. 10.1007/s11192-025-05251-z

By:

Kobayashi, Yoshihiko;
Kudo, Kuriko;
Kobayashi, Toshiya;
Kinoshita, Hiroko;
Bang, HyunJung;
Ito, Hiroshi;
Kishimura, Akihiro;
Matsumoto, Yusuke;
Miwa, Masato;
Unoki, Motoko;
Yoshioka, Tamaki

Publication type:

Article

Chromatin remodeling in replication‐uncoupled maintenance DNA methylation and chromosome stability: Insights from ICF syndrome studies.

Published in:

Genes to Cells, 2021, v. 26, n. 6, p. 349, doi. 10.1111/gtc.12850

By:

Unoki, Motoko

Publication type:

Article

Characterization of genetic‐origin‐dependent monoallelic expression in mouse embryonic stem cells.

Published in:

Genes to Cells, 2020, v. 25, n. 1, p. 54, doi. 10.1111/gtc.12736

By:

Ohishi, Hiroaki;
Au Yeung, Wan Kin;
Unoki, Motoko;
Ichiyanagi, Kenji;
Fukuda, Kei;
Maenohara, Shoji;
Shirane, Kenjiro;
Chiba, Hatsune;
Sado, Takashi;
Sasaki, Hiroyuki

Publication type:

Article

Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation.

Published in:

Genes to Cells, 2019, v. 24, n. 11, p. 746, doi. 10.1111/gtc.12723

By:

Aktar, Sharmin;
Sasaki, Hiroyuki;
Unoki, Motoko

Publication type:

Article

Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients.

Published in:

Journal of Human Genetics, 2013, v. 58, n. 7, p. 455, doi. 10.1038/jhg.2013.56

By:

Nitta, Hirohisa;
Unoki, Motoko;
Ichiyanagi, Kenji;
Kosho, Tomoki;
Shigemura, Tomonari;
Takahashi, Hiroshi;
Velasco, Guillaume;
Francastel, Claire;
Picard, Capucine;
Kubota, Takeo;
Sasaki, Hiroyuki

Publication type:

Article

The maternal protein NLRP5 stabilizes UHRF1 in the cytoplasm: implication for the pathogenesis of multilocus imprinting disturbance.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 18, p. 1575, doi. 10.1093/hmg/ddae096

By:

Unoki, Motoko;
Uemura, Shuhei;
Fujimoto, Akihiro;
Sasaki, Hiroyuki

Publication type:

Article

Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 9, p. 1439, doi. 10.1093/hmg/ddac291

By:

Unoki, Motoko;
Velasco, Guillaume;
Kori, Satomi;
Arita, Kyohei;
Daigaku, Yasukazu;
Yeung, Wan Kin Au;
Fujimoto, Akihiro;
Ohashi, Hirofumi;
Kubota, Takeo;
Miyake, Kunio;
Sasaki, Hiroyuki

Publication type:

Article

The UHRF protein family in epigenetics, development, and carcinogenesis.

Published in:

Proceedings of the Japan Academy, Series B Physical & biological sciences, 2022, v. 98, n. 8, p. 401, doi. 10.2183/pjab.98.021

By:

Motoko UNOKI;
Hiroyuki SASAKI

Publication type:

Article

Reviewing the current classification of inhibitor of growth family proteins.

Published in:

Cancer Science, 2009, v. 100, n. 7, p. 1173, doi. 10.1111/j.1349-7006.2009.01183.x

By:

Unoki, Motoko;
Kumamoto, Kensuke;
Takenoshita, Seiichi;
Harris, Curtis C.

Publication type:

Article

Inhibitory effects of extracts from Eucalyptus gunnii on α-synuclein amyloid fibrils.

Published in:

Bioscience, Biotechnology & Biochemistry, 2024, v. 88, n. 11, p. 1289, doi. 10.1093/bbb/zbae114

By:

So, Masatomo;
Ono, Misaki;
Oogai, Shigeki;
Kondo, Minako;
Yamazaki, Kaede;
Nachtegael, Charlotte;
Hamajima, Hiroshi;
Mutoh, Risa;
Kato, Masaki;
Kawate, Hisaya;
Oki, Tomoyuki;
Kawata, Yasushi;
Kumamoto, Shiho;
Tokui, Noritaka;
Takei, Toshiki;
Shimizu, Kuniyoshi;
Inoue, Akio;
Yamamoto, Naoki;
Unoki, Motoko;
Tanabe, Kenichi

Publication type:

Article

UHRF1 is essential for proper cytoplasmic architecture and function of mouse oocytes and derived embryos.

Published in:

Life Science Alliance, 2023, v. 6, n. 8, p. 1, doi. 10.26508/lsa.202301904

By:

Shuhei Uemura;
Shoji Maenohara;
Kimiko Inoue;
Narumi Ogonuki;
Shogo Matoba;
Atsuo Ogura;
Mayuko Kurumizaka;
Kazuo Yamagata;
Sharif, Jafar;
Haruhiko Koseki;
Koji Ueda;
Motoko Unoki;
Hiroyuki Sasaki

Publication type:

Article

Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association of a T924C polymorphism in the thromboxane A2 receptor gene.

Published in:

Human Genetics, 2000, v. 106, n. 4, p. 440, doi. 10.1007/s004390000267

By:

Unoki, Motoko;
Furuta, Sachiyo;
Onouchi, Yoshihiro;
Watanabe, Otsu;
Doi, Satoru;
Fujiwara, Hiroshi;
Miyatake, Akihiko;
Fujita, Kimie;
Tamari, Mayumi;
Nakamura, Yusuke

Publication type:

Article

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.

Published in:

International Journal of Cancer, 2011, v. 128, n. 3, p. 562, doi. 10.1002/ijc.25366

By:

Yoshimatsu, Masanori;
Toyokawa, Gouji;
Hayami, Shinya;
Unoki, Motoko;
Tsunoda, Tatsuhiko;
Field, Helen I.;
Kelly, John D.;
Neal, David E.;
Maehara, Yoshihiko;
Ponder, Bruce A.J.;
Nakamura, Yusuke;
Hamamoto, Ryuji

Publication type:

Article

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.

Published in:

International Journal of Cancer, 2011, v. 128, n. 3, p. 574, doi. 10.1002/ijc.25349

By:

Hayami, Shinya;
Kelly, John D.;
Cho, Hyun-Soo;
Yoshimatsu, Masanori;
Unoki, Motoko;
Tsunoda, Tatsuhiko;
Field, Helen I.;
Neal, David E.;
Yamaue, Hiroki;
Ponder, Bruce A.J.;
Nakamura, Yusuke;
Hamamoto, Ryuji

Publication type:

Article

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.

Published in:

International Journal of Cancer, 2009, v. 125, n. 6, p. 1306, doi. 10.1002/ijc.24437

By:

Kumamoto, Kensuke;
Fujita, Kaori;
Kurotani, Reiko;
Saito, Motonobu;
Unoki, Motoko;
Hagiwara, Nobutoshi;
Shiga, Hideaki;
Bowman, Elise D.;
Yanaihara, Nozomu;
Okamura, Shu;
Nagashima, Makoto;
Miyamoto, Kotaro;
Takenoshita, Seiichi;
Yokota, Jun;
Harris, Curtis C.

Publication type:

Article

Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity

Published in:

FEBS Letters, 2003, v. 554, n. 1/2, p. 67, doi. 10.1016/S0014-5793(03)01092-5

By:

Unoki, Motoko;
Nakamura, Yusuke

Publication type:

Article

CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-74636-2

By:

Unoki, Motoko;
Sharif, Jafar;
Saito, Yuichiro;
Velasco, Guillaume;
Francastel, Claire;
Koseki, Haruhiko;
Sasaki, Hiroyuki

Publication type:

Article

EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.

Published in:

Oncogene, 2003, v. 22, n. 14, p. 2172, doi. 10.1038/sj.onc.1206222

By:

Unoki, Motoko;
Nakamura, Yusuke

Publication type:

Article

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

Published in:

Oncogene, 2001, v. 20, n. 33, p. 4457, doi. 10.1038/sj.onc.1204608

By:

Unoki, Motoko;
Nakamura, Yusuke

Publication type:

Article

Ddhd1 knockout mouse as a model of locomotive and physiological abnormality in familial spastic paraplegia.

Published in:

Bioscience Reports, 2021, v. 41, n. 2, p. 1, doi. 10.1042/BSR20204171

By:

Takuya Morikawa;
Hiroaki Ohishi;
Kengo Kosaka;
Tomofumi Shimojo;
Akihiro Nagano;
Itsuki Taniguchi;
Ryuta Fujioka;
Kosei Moriyama;
Motoko Unoki;
Masatomo Takahashi;
Motonao Nakao;
Yoshihiro Izumi;
Takeshi Bamba;
Hiroyuki Sasaki;
Shiroh Miura;
Hiroki Shibata

Publication type:

Article

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

Published in:

FEBS Letters, 2012, v. 586, n. 11, p. 1570, doi. 10.1016/j.febslet.2012.04.038

By:

Mori, Tsutomu;
Ikeda, Daisuke D.;
Yamaguchi, Yoshiki;
Unoki, Motoko

Publication type:

Article

A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis

Published in:

FEBS Letters, 2008, v. 582, n. 28, p. 3868, doi. 10.1016/j.febslet.2008.10.024

By:

Unoki, Motoko;
Kumamoto, Kensuke;
Robles, Ana I.;
Shen, Jiang Cheng;
Zheng, Zhi-Ming;
Harris, Curtis C.

Publication type:

Article

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.

Published in:

PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007042

By:

Maenohara, Shoji;
Unoki, Motoko;
Toh, Hidehiro;
Ohishi, Hiroaki;
Sharif, Jafar;
Koseki, Haruhiko;
Sasaki, Hiroyuki

Publication type:

Article

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.

Published in:

Oncogene, 2004, v. 23, n. 46, p. 7601, doi. 10.1038/sj.onc.1208053

By:

Unoki, Motoko;
Nishidate, Toshihiko;
Nakamura, Yusuke

Publication type:

Article

Corrigendum: Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 12003, doi. 10.1038/ncomms12003

By:

Thijssen, Peter E.;
Ito, Yuya;
Grillo, Giacomo;
Wang, Jun;
Velasco, Guillaume;
Nitta, Hirohisa;
Unoki, Motoko;
Yoshihara, Minako;
Suyama, Mikita;
Sun, Yu;
Lemmers, Richard J. L. F.;
de Greef, Jessica C.;
Gennery, Andrew;
Picco, Paolo;
Kloeckener-Gruissem, Barbara;
Güngör, Tayfun;
Reisli, Ismail;
Picard, Capucine;
Kebaili, Kamila;
Roquelaure, Bertrand

Publication type:

Article

Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Published in:

Nature Communications, 2015, v. 6, n. 7, p. 7870, doi. 10.1038/ncomms8870

By:

Thijssen, Peter E.;
Ito, Yuya;
Grillo, Giacomo;
Wang, Jun;
Velasco, Guillaume;
Nitta, Hirohisa;
Unoki, Motoko;
Yoshihara, Minako;
Suyama, Mikita;
Sun, Yu;
Lemmers, Richard J. L. F.;
de Greef, Jessica C.;
Gennery, Andrew;
Picco, Paolo;
Kloeckener-Gruissem, Barbara;
Güngör, Tayfun;
Reisli, Ismail;
Picard, Capucine;
Kebaili, Kamila;
Roquelaure, Bertrand

Publication type:

Article

Overexpression of the JmjC histone demethylaseKDM5B in human carcinogenesis: involvement inthe proliferation of cancer cells through the E2F/RB pathway.

Published in:

Molecular Cancer, 2010, v. 9, p. 59, doi. 10.1186/1476-4598-9-59

By:

Hayami, Shinya;
Yoshimatsu, Masanori;
Veerakumarasivam, Abhimanyu;
Unoki, Motoko;
Iwai, Yukiko;
Tsunoda, Tatsuhiko;
Field, Helen I.;
Kelly, John D.;
Neal, David E.;
Yamaue, Hiroki;
Ponder, Bruce A. J.;
Nakamura, Yusuke;
Hamamoto, Ryuji

Publication type:

Article

Interplay between Histone and DNA Methylation Seen through Comparative Methylomes in Rare Mendelian Disorders.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3735, doi. 10.3390/ijms22073735

By:

Velasco, Guillaume;
Ulveling, Damien;
Rondeau, Sophie;
Marzin, Pauline;
Unoki, Motoko;
Cormier-Daire, Valérie;
Francastel, Claire;
Sadikovic, Bekim

Publication type:

Article

Long-read sequencing reveals novel isoform-specific eQTLs and regulatory mechanisms of isoform expression in human B cells.

Published in:

Genome Biology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s13059-025-03583-w

By:

Nagura, Yuya;
Shimada, Mihoko;
Kuribayashi, Ryoji;
Ikemoto, Ko;
Kiyose, Hiroki;
Igarashi, Arisa;
Kaname, Tadashi;
Unoki, Motoko;
Fujimoto, Akihiro

Publication type:

Article

Long-read sequencing reveals the complex structure of extra dic(21;21) chromosome and its biological effects.

Published in:

Human Genetics, 2023, v. 142, n. 9, p. 1375, doi. 10.1007/s00439-023-02583-9

By:

Yoshida-Tanaka, Kugui;
Ikemoto, Ko;
Kuribayashi, Ryoji;
Unoki, Motoko;
Takano, Takako;
Fujimoto, Akihiro

Publication type:

Article