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- Title
Caracterización fenotípica de la morfología facial en un grupo de población africana con fisura labio-palatina no sindrómica.
- Authors
Zamudio, Diana Constanza Borrero; Ricaurte, Susana Paola Gutiérrez; Downing, Daniela Mercedes Izaguirre; Mendoza, Liliana Margarita Otero
- Abstract
Background: Craniofacial shape of individuals with orofacial clefts is different from unaffected ones and is influenced by hereditary factors. It was suggested that the craniofacial morphology of biological parents of affected individuals may differ from the regular population. Objective: Describe the parental facial phenotype that may be related to risk of non-syndromic cleft lip/palate (NSCLP) in the offspring in an African population. Methods: 67 frontal and lateral photographs from 80 parents of children with NSCL with or without palate; 70 photographs from a control group were selected. Photos were analyzed through the Vistadent O.C. software and a screen ruler. Results: The frontal view of the facial upper third was smaller in the parental and control groups (64% and 40%). Transversally, the interlimbic distance in the study group was larger (56.7%) than the control group (37.1%) (p=0,02). When comparing cleft side and presence of lateral asymmetry, there was a larger nasal width on the left side (16 parents) and 10 of these had an offspring with left side cleft. Conclusions: Parents of children with NSCLP in this sample of African race showed phenotypic traits that differed from the control group. In the horizontal view, parents had a larger interlimbic distance that may be associated with the risk of having children with NSCLP. Vertically, a smaller facial upper third cannot be taken as a risk factor as has been taken for other race studies, as well as a large nasal width in the African race is not a risk factor, but a common trait in the African race.
- Subjects
AFRICA; FACIAL bone abnormalities; CLEFT lip; INHERITANCE &; succession; DIAGNOSTIC imaging; PATIENTS
- Publication
Universitas Odontológica, 2010, Vol 29, Issue 62, p11
- ISSN
0120-4319
- Publication type
Article