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Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.
Published in:
Journal of Pathology, 2016, v. 239, n. 1, p. 109, doi. 10.1002/path.4707
By:
- Wilhelm, Annika;
- Shepherd, Emma L;
- Amatucci, Aldo;
- Munir, Mamoona;
- Reynolds, Gary;
- Humphreys, Elizabeth;
- Resheq, Yazid;
- Adams, David H;
- Hübscher, Stefan;
- Burkly, Linda C;
- Weston, Christopher J;
- Afford, Simon C
Publication type:
Article
How Machine Perfusion Ameliorates Hepatic Ischaemia Reperfusion Injury.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7523, doi. 10.3390/ijms22147523
By:
- Clarke, George;
- Mergental, Hynek;
- Hann, Angus;
- Perera, M. Thamara P. R.;
- Afford, Simon C.;
- Mirza, Darius F.
Publication type:
Article
Biomarkers of Liver Injury during Transplantation in an Era of Machine Perfusion.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1578, doi. 10.3390/ijms21051578
By:
- Bhogal, Ricky H.;
- Mirza, Darius F.;
- Afford, Simon C.;
- Mergental, Hynek
Publication type:
Article
Anti-oxidants do not prevent bile acid-induced cell death in rat hepatocytes.
Published in:
Liver International, 2011, v. 31, n. 2, p. 273, doi. 10.1111/j.1478-3231.2010.02372.x
By:
- Bhogal, Ricky H.;
- Afford, Simon C.
Publication type:
Article
Lactate measurements in an integrated perfusion machine for human livers.
Published in:
2020
By:
- Stephenson, Barney T. F.;
- Afford, Simon C.;
- Mergental, Hynek;
- Mirza, Darius F.
Publication type:
Letter
Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis.
Published in:
Journal of Pathology, 1998, v. 186, n. 1, p. 82, doi. 10.1002/(SICI)1096-9896(199809)186:1<82::AID-PATH151>3.0.CO;2-D
By:
- Afford, Simon C.;
- Fisher, Neil C.;
- Neil, Desley A. H.;
- Fear, Janine;
- Brun, Paoula;
- Hubscher, Stefan G.;
- Adams, David H.
Publication type:
Article
Apoptosis in the human liver during allograft rejection and end-stage liver disease.
Published in:
Journal of Pathology, 1995, v. 176, n. 4, p. 373, doi. 10.1002/path.1711760408
By:
- Afford, Simon C.;
- Hubscher, Stefan;
- Strain, Alastair J.;
- Adams, David H.;
- Neuberger, James M.
Publication type:
Article
Pertussis Toxin, an Inhibitor of Gαi PCR, Inhibits Bile Acid-and Cytokine-Induced Apoptosis in Primary Rat Hepatocytes.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043156
By:
- Karimian, Golnar;
- Buist-Homan, Manon;
- Faber, Klaas Nico;
- Moshage, Han;
- Afford, Simon
Publication type:
Article
Activation of CD40 with Platelet Derived CD154 Promotes Reactive Oxygen Species Dependent Death of Human Hepatocytes during Hypoxia and Reoxygenation.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030867
By:
- Bhogal, Ricky H.;
- Weston, Christopher J.;
- Curbishley, Stuart M.;
- Adams, David H.;
- Afford, Simon C.
Publication type:
Article
Isolation of Primary Human Hepatocytes from Normal and Diseased Liver Tissue: A One Hundred Liver Experience.
Published in:
PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018222
By:
- Bhogal, Ricky H.;
- Hodson, James;
- Bartlett, David C.;
- Weston, Christopher J.;
- Curbishley, Stuart M.;
- Haughton, Emma;
- Williams, Kevin T.;
- Reynolds, Gary M.;
- Newsome, Phillip N.;
- Adams, David H.;
- Afford, Simon C.
Publication type:
Article
Primary and Malignant Cholangiocytes Undergo CD40 Mediated Fas Dependent Apoptosis, but Are Insensitive to Direct Activation with Exogenous Fas Ligand.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014037
By:
- Humphreys, Elizabeth H.;
- Williams, Kevin T.;
- Adams, David H.;
- Afford, Simon C.
Publication type:
Article
Differential Expression of HGF and Met in Human Placenta.
Published in:
Journal of Clinical Endocrinology & Metabolism, 1998, v. 83, n. 4, p. 1400, doi. 10.1210/jcem.83.4.4734-9
By:
- Somerset, David A.;
- Kilby, Mark D.;
- Strain, Alastair J.;
- Afford, Simon
Publication type:
Article
The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01226
By:
- Laing, Richard W.;
- Stubblefield, Samantha;
- Wallace, Lorraine;
- Roobrouck, Valerie D.;
- Bhogal, Ricky H.;
- Schlegel, Andrea;
- Boteon, Yuri L.;
- Reynolds, Gary M.;
- Ting, Anthony E.;
- Mirza, Darius F.;
- Newsome, Philip N.;
- Mergental, Hynek;
- Afford, Simon C.
Publication type:
Article
Correction: Lertsuwan et al. CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. Cancers 2018, 10 , 283.
Published in:
2023
By:
- Lertsuwan, Jomnarong;
- Lertsuwan, Kornkamon;
- Sawasdichai, Anyaporn;
- Tasnawijitwong, Nathapol;
- Lee, Ka Ying;
- Kitchen, Philip;
- Afford, Simon;
- Gaston, Kevin;
- Jayaraman, Padma-Sheela;
- Satayavivad, Jutamaad
Publication type:
Correction Notice
CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism.
Published in:
Cancers, 2018, v. 10, n. 9, p. 283, doi. 10.3390/cancers10090283
By:
- Lertsuwan, Jomnarong;
- Lertsuwan, Kornkamon;
- Sawasdichai, Anyaporn;
- Tasnawijitwong, Nathapol;
- Lee, Ka Ying;
- Kitchen, Philip;
- Afford, Simon;
- Gaston, Kevin;
- Jayaraman, Padma-Sheela;
- Satayavivad, Jutamaad
Publication type:
Article
Correction: The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
Published in:
2020
By:
- Boteon, Yuri L.;
- Laing, Richard W.;
- Schlegel, Andrea;
- Wallace, Lorraine;
- Smith, Amanda;
- Attard, Joseph;
- Bhogal, Ricky H.;
- Reynolds, Gary;
- Thamara PR Perera, M.;
- Muiesan, Paolo;
- Mirza, Darius F.;
- Mergental, Hynek;
- Afford, Simon C.
Publication type:
Correction Notice
The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver.
Published in:
PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0224066
By:
- Boteon, Yuri L.;
- Laing, Richard W.;
- Schlegel, Andrea;
- Wallace, Lorraine;
- Smith, Amanda;
- Attard, Joseph;
- Bhogal, Ricky H.;
- Reynolds, Gary;
- PR Perera, M. Thamara;
- Muiesan, Paolo;
- Mirza, Darius F.;
- Mergental, Hynek;
- Afford, Simon C.
Publication type:
Article
Hepatocyte Growth Factor Concentration in Maternal and Umbilical Cord Blood Samples and Expression in Fetal Liver.
Published in:
Reproductive Sciences, 2000, v. 7, n. 6, p. 333, doi. 10.1177/107155760000700603
By:
- Somerset, David A.;
- Jauniaux, Eric;
- Strain, Alastair J.;
- Afford, Simon;
- Kilby, Mark D.
Publication type:
Article
Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H–R)
Published in:
FEBS Letters, 2011, v. 585, n. 6, p. 935, doi. 10.1016/j.febslet.2011.02.030
By:
- Bhogal, Ricky H.;
- Weston, Christopher J.;
- Curbishley, Stuart M.;
- Bhatt, Anand N.;
- Adams, David H.;
- Afford, Simon C.
Publication type:
Article
Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation.
Published in:
Transplant International, 1998, v. 11, n. 4, p. 288, doi. 10.1111/j.1432-2277.1998.tb00973.x
By:
- Xu, Min;
- Pirenne, Jacques;
- Antoniou, Efstathios A;
- Afford, Simon C;
- D'Silva, Milbhor;
- McMaster, Paul
Publication type:
Article
The Meckel–Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.
Published in:
Human Molecular Genetics, 2007, v. 16, n. 2, p. 173, doi. 10.1093/hmg/ddl459
By:
- Dawe, Helen R.;
- Smith, Ursula M.;
- Cullinane, Andrew R.;
- Gerrelli, Dianne;
- Cox, Phillip;
- Badano, Jose L.;
- Blair-Reid, Sarah;
- Sriram, Nisha;
- Katsanis, Nicholas;
- Attie-Bitach, Tania;
- Afford, Simon C.;
- Copp, Andrew J.;
- Kelly, Deirdre A.;
- Gull, Keith;
- Johnson, Colin A.
Publication type:
Article
An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells.
Published in:
PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0201419
By:
- Boteon, Yuri L.;
- Wallace, Lorraine;
- Boteon, Amanda P. C. S.;
- Mirza, Darius F.;
- Mergental, Hynek;
- Bhogal, Ricky H.;
- Afford, Simon
Publication type:
Article
N-acetylcysteine: a novel approach to methaemoglobinaemia in normothermic liver machine perfusion.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45206-z
By:
- Clarke, George;
- Mao, Jingwen;
- Fan, Yiyu;
- Hann, Angus;
- Gupta, Amita;
- Nutu, Anisa;
- Buckel, Erwin;
- Kayani, Kayani;
- Murphy, Nicholas;
- Bangash, Mansoor N.;
- Casey, Anna L.;
- Wootton, Isla;
- Lawson, Alexander J.;
- Dasari, Bobby V. M.;
- Perera, M. Thamara P. R.;
- Mergental, Hynek;
- Afford, Simon C.
Publication type:
Article
Reply to 'Hypothermic machine perfusion before viability testing of previously discarded human livers'.
Published in:
2021
By:
- Mergental, Hynek;
- Laing, Richard W.;
- Afford, Simon C.;
- Mirza, Darius F.
Publication type:
Letter
Regulation of α1-Antitrypsin Synthesis by Granulocyte Macrophage Colony-Stimulating Factor in the U937 Promonocytic Cell Line.
Published in:
Biological Chemistry, 1992, v. 373, n. 1, p. 219
By:
- AFFORD, Simon C.;
- BURNETT, David;
- STOCKLEY, Robert A.
Publication type:
Article
The Assessment of α1Proteinase Inhibitor Form and Function in Lung Lavage Fluid from Healthy Subjects.
Published in:
Biological Chemistry, 1988, v. 369, n. 2, p. 1065
By:
- AFFORD, Simon C.;
- BURNETT, David;
- CAMPBELL, Edward J.;
- CURY, James Davis;
- STOCKLEY, Robert A.
Publication type:
Article

Found: 26

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.

How Machine Perfusion Ameliorates Hepatic Ischaemia Reperfusion Injury.

Biomarkers of Liver Injury during Transplantation in an Era of Machine Perfusion.

Anti-oxidants do not prevent bile acid-induced cell death in rat hepatocytes.

Lactate measurements in an integrated perfusion machine for human livers.

Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis.

Apoptosis in the human liver during allograft rejection and end-stage liver disease.

Pertussis Toxin, an Inhibitor of G<sub>αi</sub> PCR, Inhibits Bile Acid-and Cytokine-Induced Apoptosis in Primary Rat Hepatocytes.

Activation of CD40 with Platelet Derived CD154 Promotes Reactive Oxygen Species Dependent Death of Human Hepatocytes during Hypoxia and Reoxygenation.

Isolation of Primary Human Hepatocytes from Normal and Diseased Liver Tissue: A One Hundred Liver Experience.

Primary and Malignant Cholangiocytes Undergo CD40 Mediated Fas Dependent Apoptosis, but Are Insensitive to Direct Activation with Exogenous Fas Ligand.

Differential Expression of HGF and Met in Human Placenta.

The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion.

Correction: Lertsuwan et al. CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. Cancers 2018, 10 , 283.

CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism.

Correction: The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver

The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver.

Hepatocyte Growth Factor Concentration in Maternal and Umbilical Cord Blood Samples and Expression in Fetal Liver.

Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H–R)

Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation.

The Meckel–Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells.

N-acetylcysteine: a novel approach to methaemoglobinaemia in normothermic liver machine perfusion.

Reply to 'Hypothermic machine perfusion before viability testing of previously discarded human livers'.

Regulation of α<sub>1</sub>-Antitrypsin Synthesis by Granulocyte Macrophage Colony-Stimulating Factor in the U937 Promonocytic Cell Line.

The Assessment of α<sub>1</sub>Proteinase Inhibitor Form and Function in Lung Lavage Fluid from Healthy Subjects.