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- Title
Exploration of new reaction tools for late-stage functionalization of complex chemicals.
- Authors
Dominguez-Huerta, Alejandra; Dai, Xi-Jie; Zhou, Feng; Querard, Pierre; Qiu, Zihang; Ung, Sosthene; Liu, Wenbo; Li, Jianbin; Li, Chao-Jun
- Abstract
Chemistry has always had as a target the conversion of molecules into valuable materials. Nevertheless, the aim of past synthesis has primarily focused on achieving a given transformation, regardless of the environmental impact of the synthetic route. Given the current global situation, the demand for sustainable alternatives has substantially increased. Our group focuses on developing selective chemical transformations that benefit from mild conditions, improved atom economy, and that can make use of renewable feedstocks as starting materials. This account summarizes our work over the past two decades specifically regarding the selective removal, conversion, and addition of functional groups that can, later on, be applied at a late stage for the modification of complex molecules.
- Subjects
CHEMICAL reactions; ENVIRONMENTAL impact analysis; SUSTAINABILITY; RENEWABLE natural resources; NANOPARTICLES
- Publication
Canadian Journal of Chemistry, 2019, Vol 97, Issue 2, p67
- ISSN
0008-4042
- Publication type
Article
- DOI
10.1139/cjc-2018-0357