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- Title
Association of Genital Infection with Specific Chlamydia trachomatis Serovars and Race.
- Authors
Workowski, Kimberly A.; Suchland, Robert J.; Pettinger, Mary B.; Stamm, Walter E.
- Abstract
Black race is an important risk marker for Chlamydia trachomatis genital infection. To define whether C. trachomatis serovars differ by ethnic distribution, a panel of monoclonal antibodies was used to serotype 934 urethral and 581 cervical isolates from patients attending a sexually transmitted diseases clinic over 2 years. The overall serovar distribution in cervical and urethral infections was comparable, with B class serovars predominating. Significantly higher inclusion counts were observed both in younger women and in nonblacks regardless ofserovar. Serovar D was less frequent among blacks at the urethral site (P = .001), while serovar Ia was more frequent in blacks at both sites (urethral, P < .001; cervical, P = .02). These associations remained significant after adjusting for age and number of inclusion-forming units by multivariate analysis. Thus, specific serovars may be associated with particular racial groups; either behavioral or biologic factors could explain these findings.
- Publication
Journal of Infectious Diseases, 1992, Vol 166, Issue 6, p1445
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1093/infdis/166.6.1445