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- Title
Bacterial morphogenesis and the enigmatic MreB helix.
- Authors
Errington, Jeff
- Abstract
Work over the past decade has highlighted the pivotal role of the actin-like MreB family of proteins in the determination and maintenance of rod cell shape in bacteria. Early images of MreB localization revealed long helical filaments, which were suggestive of a direct role in governing cell wall architecture. However, several more recent, higher-resolution studies have questioned the existence or importance of the helical structures. In this Opinion article, I navigate a path through these conflicting reports, revive the helix model and summarize the key questions that remain to be answered.
- Subjects
ACTIN; BACTERIA; BACTERIAL cell walls; HELICAL structure; DECAPENTAPLEGIC protein
- Publication
Nature Reviews Microbiology, 2015, Vol 13, Issue 4, p241
- ISSN
1740-1526
- Publication type
Article
- DOI
10.1038/nrmicro3398