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- Title
CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents.
- Authors
Houssier, Marianne; Raoul, William; Lavalette, Sophie; Keller, Nicole; Guillonneau, Xavier; Baragatti, Barbara; Jonet, Laurent; Jeanny, Jean-Claude; Behar-Cohen, Francine; Coceani, Flavio; Scherman, Daniel; Lachapelle, Pierre; Huy Ong; Chemtob, Sylvain; Sennlaub, Florian
- Abstract
Florian Sennelaub and colleagues show that CD36 deficiency leads to choroidal involution, a key feature of "dry" age-related macular degeneration, via COX-2 down-regulation in the retinal pigment epithelium.
- Subjects
CHOROID diseases; CHOROID; SENNELAUB, Florian; RETINAL degeneration; RODENTS
- Publication
PLoS Medicine, 2008, Vol 5, Issue 2, pe39
- ISSN
1549-1277
- Publication type
Article
- DOI
10.1371/journal.pmed.0050039